Increased Incidence of Antimicrobial-Resistant Nontyphoidal Salmonella Infections, United States, 2004–2016
Salmonella is a major cause of foodborne illness in the United States, and antimicrobial-resistant strains pose a serious threat to public health. We used Bayesian hierarchical models of culture-confirmed infections during 2004–2016 from 2 Centers for Disease Control and Prevention surveillance syst...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2021-06-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/27/6/20-4486_article |
| _version_ | 1818562954958733312 |
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| author | Felicita Medalla Weidong Gu Cindy R. Friedman Michael Judd Jason Folster Patricia M. Griffin Robert M. Hoekstra |
| author_facet | Felicita Medalla Weidong Gu Cindy R. Friedman Michael Judd Jason Folster Patricia M. Griffin Robert M. Hoekstra |
| author_sort | Felicita Medalla |
| collection | DOAJ |
| description | Salmonella is a major cause of foodborne illness in the United States, and antimicrobial-resistant strains pose a serious threat to public health. We used Bayesian hierarchical models of culture-confirmed infections during 2004–2016 from 2 Centers for Disease Control and Prevention surveillance systems to estimate changes in the national incidence of resistant nontyphoidal Salmonella infections. Extrapolating to the United States population and accounting for unreported infections, we estimated a 40% increase in the annual incidence of infections with clinically important resistance (resistance to ampicillin or ceftriaxone or nonsusceptibility to ciprofloxacin) during 2015–2016 (≈222,000 infections) compared with 2004–2008 (≈159,000 infections). Changes in the incidence of resistance varied by serotype. Serotypes I 4,[5],12:i:- and Enteritidis were responsible for two thirds of the increased incidence of clinically important resistance during 2015–2016. Ciprofloxacin-nonsusceptible infections accounted for more than half of the increase. These estimates can help in setting targets and priorities for prevention. |
| first_indexed | 2024-12-14T01:10:31Z |
| format | Article |
| id | doaj.art-91f6ab3f55fb4510b01e3cb8987da3d9 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-12-14T01:10:31Z |
| publishDate | 2021-06-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-91f6ab3f55fb4510b01e3cb8987da3d92022-12-21T23:22:45ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592021-06-012761662167210.3201/eid2706.204486Increased Incidence of Antimicrobial-Resistant Nontyphoidal Salmonella Infections, United States, 2004–2016Felicita MedallaWeidong GuCindy R. FriedmanMichael JuddJason FolsterPatricia M. GriffinRobert M. HoekstraSalmonella is a major cause of foodborne illness in the United States, and antimicrobial-resistant strains pose a serious threat to public health. We used Bayesian hierarchical models of culture-confirmed infections during 2004–2016 from 2 Centers for Disease Control and Prevention surveillance systems to estimate changes in the national incidence of resistant nontyphoidal Salmonella infections. Extrapolating to the United States population and accounting for unreported infections, we estimated a 40% increase in the annual incidence of infections with clinically important resistance (resistance to ampicillin or ceftriaxone or nonsusceptibility to ciprofloxacin) during 2015–2016 (≈222,000 infections) compared with 2004–2008 (≈159,000 infections). Changes in the incidence of resistance varied by serotype. Serotypes I 4,[5],12:i:- and Enteritidis were responsible for two thirds of the increased incidence of clinically important resistance during 2015–2016. Ciprofloxacin-nonsusceptible infections accounted for more than half of the increase. These estimates can help in setting targets and priorities for prevention.https://wwwnc.cdc.gov/eid/article/27/6/20-4486_articleSalmonellanontyphoidalantimicrobial resistanceantibiotic resistancedrug resistanceceftriaxone |
| spellingShingle | Felicita Medalla Weidong Gu Cindy R. Friedman Michael Judd Jason Folster Patricia M. Griffin Robert M. Hoekstra Increased Incidence of Antimicrobial-Resistant Nontyphoidal Salmonella Infections, United States, 2004–2016 Emerging Infectious Diseases Salmonella nontyphoidal antimicrobial resistance antibiotic resistance drug resistance ceftriaxone |
| title | Increased Incidence of Antimicrobial-Resistant Nontyphoidal Salmonella Infections, United States, 2004–2016 |
| title_full | Increased Incidence of Antimicrobial-Resistant Nontyphoidal Salmonella Infections, United States, 2004–2016 |
| title_fullStr | Increased Incidence of Antimicrobial-Resistant Nontyphoidal Salmonella Infections, United States, 2004–2016 |
| title_full_unstemmed | Increased Incidence of Antimicrobial-Resistant Nontyphoidal Salmonella Infections, United States, 2004–2016 |
| title_short | Increased Incidence of Antimicrobial-Resistant Nontyphoidal Salmonella Infections, United States, 2004–2016 |
| title_sort | increased incidence of antimicrobial resistant nontyphoidal salmonella infections united states 2004 2016 |
| topic | Salmonella nontyphoidal antimicrobial resistance antibiotic resistance drug resistance ceftriaxone |
| url | https://wwwnc.cdc.gov/eid/article/27/6/20-4486_article |
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