Dynamic feedback regulation for efficient membrane protein production using a small RNA-based genetic circuit in Escherichia coli

Dynamic feedback regulation for efficient membrane protein production using a small RNA-based genetic circuit in Escherichia coli

Abstract Background Membrane proteins (MPs) are an important class of molecules with a wide array of cellular functions and are part of many metabolic pathways. Despite their great potential—as therapeutic drug targets or in microbial cell factory optimization—many challenges remain for efficient an...

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Bibliographic Details
Main Authors: Chiara Guidi, Lien De Wannemaeker, Jasmine De Baets, Wouter Demeester, Jo Maertens, Brecht De Paepe, Marjan De Mey
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Microbial Cell Factories
Subjects:
Membrane proteins
Escherichia coli
sRNA-based genetic circuitry
Industrial biotechnology
Online Access:https://doi.org/10.1186/s12934-022-01983-2

Internet

https://doi.org/10.1186/s12934-022-01983-2

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