Pulse Oximetry and Congenital Heart Disease Screening: Results of the First Pilot Study in Morocco
Congenital heart disease (CHD) is the most common congenital malformation. Diagnosis of critical congenital heart disease (CCHD), the most severe type of congenital heart disease, in a newborn may be difficult. The addition of CCHD screening, using pulse oximetry, to clinical assessment significantl...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-06-01
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| Series: | International Journal of Neonatal Screening |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2409-515X/6/3/53 |
| _version_ | 1797563658847387648 |
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| author | Nadia El Idrissi Slitine Fatiha Bennaoui Craig A. Sable Gerard R. Martin Lisa A. Hom Amal Fadel Soufiane Moussaoui Nadir Inajjarne Drissi Boumzebra Youssef Mouaffak Said Younous Lahcen Boukhanni Fadl Mrabih Rabou Maoulainine |
| author_facet | Nadia El Idrissi Slitine Fatiha Bennaoui Craig A. Sable Gerard R. Martin Lisa A. Hom Amal Fadel Soufiane Moussaoui Nadir Inajjarne Drissi Boumzebra Youssef Mouaffak Said Younous Lahcen Boukhanni Fadl Mrabih Rabou Maoulainine |
| author_sort | Nadia El Idrissi Slitine |
| collection | DOAJ |
| description | Congenital heart disease (CHD) is the most common congenital malformation. Diagnosis of critical congenital heart disease (CCHD), the most severe type of congenital heart disease, in a newborn may be difficult. The addition of CCHD screening, using pulse oximetry, to clinical assessment significantly improves the rate of detection. We conducted a pilot study in Morocco on screening neonates for critical congenital heart disease. This study was conducted in the maternity ward of Mohammed VI University Hospital of Marrakesh, Morocco, and included asymptomatic newborns delivered between March 2019 and January 2020. The screening of CCHD was performed by pulse oximetry measuring the pre- and post-ductal saturation. Screening was performed on 8013/10,451 (76.7%) asymptomatic newborns. According to the algorithm, 7998 cases passed the screening test (99.82%), including one inconclusive test that was repeated an hour later and was normal. Fifteen newborns failed the screening test (0.18%): five CCHD, five false positives, and five CHD but non-critical. One false negative case was diagnosed at 2 months of age. Our results encourage us to strengthen screening for CCHD by adding pulse oximetry to the routine newborn screening panel. |
| first_indexed | 2024-03-10T18:46:37Z |
| format | Article |
| id | doaj.art-91fc999c8ac94a3480b6282f24847fa8 |
| institution | Directory Open Access Journal |
| issn | 2409-515X |
| language | English |
| last_indexed | 2024-03-10T18:46:37Z |
| publishDate | 2020-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Neonatal Screening |
| spelling | doaj.art-91fc999c8ac94a3480b6282f24847fa82023-11-20T05:29:33ZengMDPI AGInternational Journal of Neonatal Screening2409-515X2020-06-01635310.3390/ijns6030053Pulse Oximetry and Congenital Heart Disease Screening: Results of the First Pilot Study in MoroccoNadia El Idrissi Slitine0Fatiha Bennaoui1Craig A. Sable2Gerard R. Martin3Lisa A. Hom4Amal Fadel5Soufiane Moussaoui6Nadir Inajjarne7Drissi Boumzebra8Youssef Mouaffak9Said Younous10Lahcen Boukhanni11Fadl Mrabih Rabou Maoulainine12Neonatal Intensive Care Unit, Mother and Child Hospital, Mohammed VI University Hospital, Marrakech 40000, MoroccoNeonatal Intensive Care Unit, Mother and Child Hospital, Mohammed VI University Hospital, Marrakech 40000, MoroccoChildren’s National Heart Institute, George Washington University School of Medicine, Washington, DC 20010, USAChildren’s National Heart Institute, George Washington University School of Medicine, Washington, DC 20010, USAChildren’s National Heart Institute, George Washington University School of Medicine, Washington, DC 20010, USANeonatal Intensive Care Unit, Mother and Child Hospital, Mohammed VI University Hospital, Marrakech 40000, MoroccoNeonatal Intensive Care Unit, Mother and Child Hospital, Mohammed VI University Hospital, Marrakech 40000, MoroccoNeonatal Intensive Care Unit, Mother and Child Hospital, Mohammed VI University Hospital, Marrakech 40000, MoroccoCardio-Vascular Surgery Center, Arazzi Hospital, Mohammed VI University Hospital, Marrakech 40000, MoroccoLaboratory Childhood, Health and Development, Marrakesh Medical School, Cadi Ayyad University, Marrakech 40000, MoroccoLaboratory Childhood, Health and Development, Marrakesh Medical School, Cadi Ayyad University, Marrakech 40000, MoroccoGyneco-Obstetrical Unit, Mother and Child Hospital, Mohammed VI University Hospital, Marrakech 40000, MoroccoNeonatal Intensive Care Unit, Mother and Child Hospital, Mohammed VI University Hospital, Marrakech 40000, MoroccoCongenital heart disease (CHD) is the most common congenital malformation. Diagnosis of critical congenital heart disease (CCHD), the most severe type of congenital heart disease, in a newborn may be difficult. The addition of CCHD screening, using pulse oximetry, to clinical assessment significantly improves the rate of detection. We conducted a pilot study in Morocco on screening neonates for critical congenital heart disease. This study was conducted in the maternity ward of Mohammed VI University Hospital of Marrakesh, Morocco, and included asymptomatic newborns delivered between March 2019 and January 2020. The screening of CCHD was performed by pulse oximetry measuring the pre- and post-ductal saturation. Screening was performed on 8013/10,451 (76.7%) asymptomatic newborns. According to the algorithm, 7998 cases passed the screening test (99.82%), including one inconclusive test that was repeated an hour later and was normal. Fifteen newborns failed the screening test (0.18%): five CCHD, five false positives, and five CHD but non-critical. One false negative case was diagnosed at 2 months of age. Our results encourage us to strengthen screening for CCHD by adding pulse oximetry to the routine newborn screening panel.https://www.mdpi.com/2409-515X/6/3/53neonatal screeningcongenital heart diseasepulse oximetrytelemedicineMohammed VI HospitalMarrakesh |
| spellingShingle | Nadia El Idrissi Slitine Fatiha Bennaoui Craig A. Sable Gerard R. Martin Lisa A. Hom Amal Fadel Soufiane Moussaoui Nadir Inajjarne Drissi Boumzebra Youssef Mouaffak Said Younous Lahcen Boukhanni Fadl Mrabih Rabou Maoulainine Pulse Oximetry and Congenital Heart Disease Screening: Results of the First Pilot Study in Morocco International Journal of Neonatal Screening neonatal screening congenital heart disease pulse oximetry telemedicine Mohammed VI Hospital Marrakesh |
| title | Pulse Oximetry and Congenital Heart Disease Screening: Results of the First Pilot Study in Morocco |
| title_full | Pulse Oximetry and Congenital Heart Disease Screening: Results of the First Pilot Study in Morocco |
| title_fullStr | Pulse Oximetry and Congenital Heart Disease Screening: Results of the First Pilot Study in Morocco |
| title_full_unstemmed | Pulse Oximetry and Congenital Heart Disease Screening: Results of the First Pilot Study in Morocco |
| title_short | Pulse Oximetry and Congenital Heart Disease Screening: Results of the First Pilot Study in Morocco |
| title_sort | pulse oximetry and congenital heart disease screening results of the first pilot study in morocco |
| topic | neonatal screening congenital heart disease pulse oximetry telemedicine Mohammed VI Hospital Marrakesh |
| url | https://www.mdpi.com/2409-515X/6/3/53 |
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