Effects of Unrestricted Kinematically Aligned Total Knee Arthroplasty with a Modified Soft-Tissue Respecting Technique on the Deformity of Limb Alignment in Japanese Patients

<i>Background and Objectives</i>: Unrestricted kinematic alignment total knee arthroplasty (KA-TKA) with a soft-tissue respecting technique (STRT) is a soft-tissue-dependent tibial resection entailing the restoration of the original soft-tissue tension using ligamentotaxis after resurfac...

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Main Authors: Masahiro Ishikawa, Masaaki Ishikawa, Hideaki Nagashima, Shinya Ishizuka, Kazuhiko Michishita, Yoshinori Soda, Takafumi Hiranaka
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/59/11/1969
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author Masahiro Ishikawa
Masaaki Ishikawa
Hideaki Nagashima
Shinya Ishizuka
Kazuhiko Michishita
Yoshinori Soda
Takafumi Hiranaka
author_facet Masahiro Ishikawa
Masaaki Ishikawa
Hideaki Nagashima
Shinya Ishizuka
Kazuhiko Michishita
Yoshinori Soda
Takafumi Hiranaka
author_sort Masahiro Ishikawa
collection DOAJ
description <i>Background and Objectives</i>: Unrestricted kinematic alignment total knee arthroplasty (KA-TKA) with a soft-tissue respecting technique (STRT) is a soft-tissue-dependent tibial resection entailing the restoration of the original soft-tissue tension using ligamentotaxis after resurfacing the femur, based on the concept of restoring the native or pre-osteoarthritis alignment in each patient. However, there is no consensus on the indications of unrestricted KA-TKA with the STRT. We modified the STRT, followed by an investigation of the effects of surgery on the postoperative hip–knee–ankle angle (HKAA). <i>Materials and Methods</i>: We retrospectively analyzed the clinical background data, including the preoperative and postoperative HKAA, of 87 patients who underwent unrestricted KA-TKA with the modified STRT. Univariate and multivariate analyses were performed to determine the factors affecting the postoperative HKAA. A receiver operating characteristic (ROC) curve was plotted to investigate the change in the cut-off values of preoperative HKAA with respect to the safe zone of the postoperative HKAA. We generated two regression models, the linear regression model and generalized additive model (GAM) using machine learning, to predict the postoperative HKAA. <i>Results</i>: Univariate and multivariate analyses revealed the preoperative HKAA as the factor most relevant to the postoperative HKAA. ROC analysis revealed that the preoperative HKAA exhibited a high predictive utility, with a cut-off value of −10°, when the safe range of postoperative HKAA was set at ±5°. The GAM was the superior machine learning model, indicating a non-linear association between the preoperative and postoperative HKAA. Patients with preoperative HKAAs ranging from −18° to 4° were more likely to fall within the ±5° safe range of the postoperative HKAA. <i>Conclusions</i>: The preoperative HKAA influences the postoperative HKAA in unrestricted KA-TKA with the modified STRT. Machine learning using the GAM may contribute to the selection of patients eligible for the surgical approach.
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spelling doaj.art-9200b29db05b44c09e4352ce90672a042023-11-24T14:54:52ZengMDPI AGMedicina1010-660X1648-91442023-11-015911196910.3390/medicina59111969Effects of Unrestricted Kinematically Aligned Total Knee Arthroplasty with a Modified Soft-Tissue Respecting Technique on the Deformity of Limb Alignment in Japanese PatientsMasahiro Ishikawa0Masaaki Ishikawa1Hideaki Nagashima2Shinya Ishizuka3Kazuhiko Michishita4Yoshinori Soda5Takafumi Hiranaka6Department of Orthopedic Surgery, Nagahama Red Cross Hospital, Miyamae Nagahama, Nagahama 526-0053, Shiga, JapanDepartment of Otolaryngology, Head and Neck Surgery, Hyogo Prefectural Amagasaki General Medical Center, 2-17-77 Higashinaniwachou, Amagasaki 660-8550, Hyogo, JapanDepartment of Orthopedic Surgery, Nagahama Red Cross Hospital, Miyamae Nagahama, Nagahama 526-0053, Shiga, JapanDepartment of Orthopedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumaicho Shouwaku Nagoya, Nagoya 466-8550, Aichi, JapanDepartment of Orthopedic Surgery, Japan Community Healthcare Organization, Yugawara Hospital, Yugawara 259-0396, Kanagawa, JapanDepartment of Joint Reconstruction and Arthroscopy Center, Midorii Orthopedics, 6-35-1 Midorii, Asaminami-ku, Hiroshima City 731-0103, Hiroshima, JapanDepartment of Orthopedic Surgery and Joint Surgery Centre, Takatsuki General Hospital, 1-3-13 Kosobe-Cho, Osaka 569-1192, Osaka, Japan<i>Background and Objectives</i>: Unrestricted kinematic alignment total knee arthroplasty (KA-TKA) with a soft-tissue respecting technique (STRT) is a soft-tissue-dependent tibial resection entailing the restoration of the original soft-tissue tension using ligamentotaxis after resurfacing the femur, based on the concept of restoring the native or pre-osteoarthritis alignment in each patient. However, there is no consensus on the indications of unrestricted KA-TKA with the STRT. We modified the STRT, followed by an investigation of the effects of surgery on the postoperative hip–knee–ankle angle (HKAA). <i>Materials and Methods</i>: We retrospectively analyzed the clinical background data, including the preoperative and postoperative HKAA, of 87 patients who underwent unrestricted KA-TKA with the modified STRT. Univariate and multivariate analyses were performed to determine the factors affecting the postoperative HKAA. A receiver operating characteristic (ROC) curve was plotted to investigate the change in the cut-off values of preoperative HKAA with respect to the safe zone of the postoperative HKAA. We generated two regression models, the linear regression model and generalized additive model (GAM) using machine learning, to predict the postoperative HKAA. <i>Results</i>: Univariate and multivariate analyses revealed the preoperative HKAA as the factor most relevant to the postoperative HKAA. ROC analysis revealed that the preoperative HKAA exhibited a high predictive utility, with a cut-off value of −10°, when the safe range of postoperative HKAA was set at ±5°. The GAM was the superior machine learning model, indicating a non-linear association between the preoperative and postoperative HKAA. Patients with preoperative HKAAs ranging from −18° to 4° were more likely to fall within the ±5° safe range of the postoperative HKAA. <i>Conclusions</i>: The preoperative HKAA influences the postoperative HKAA in unrestricted KA-TKA with the modified STRT. Machine learning using the GAM may contribute to the selection of patients eligible for the surgical approach.https://www.mdpi.com/1648-9144/59/11/1969total knee arthroplastyunrestricted kinematically aligned TKAkinematic alignmentsoft-tissue respecting technique
spellingShingle Masahiro Ishikawa
Masaaki Ishikawa
Hideaki Nagashima
Shinya Ishizuka
Kazuhiko Michishita
Yoshinori Soda
Takafumi Hiranaka
Effects of Unrestricted Kinematically Aligned Total Knee Arthroplasty with a Modified Soft-Tissue Respecting Technique on the Deformity of Limb Alignment in Japanese Patients
Medicina
total knee arthroplasty
unrestricted kinematically aligned TKA
kinematic alignment
soft-tissue respecting technique
title Effects of Unrestricted Kinematically Aligned Total Knee Arthroplasty with a Modified Soft-Tissue Respecting Technique on the Deformity of Limb Alignment in Japanese Patients
title_full Effects of Unrestricted Kinematically Aligned Total Knee Arthroplasty with a Modified Soft-Tissue Respecting Technique on the Deformity of Limb Alignment in Japanese Patients
title_fullStr Effects of Unrestricted Kinematically Aligned Total Knee Arthroplasty with a Modified Soft-Tissue Respecting Technique on the Deformity of Limb Alignment in Japanese Patients
title_full_unstemmed Effects of Unrestricted Kinematically Aligned Total Knee Arthroplasty with a Modified Soft-Tissue Respecting Technique on the Deformity of Limb Alignment in Japanese Patients
title_short Effects of Unrestricted Kinematically Aligned Total Knee Arthroplasty with a Modified Soft-Tissue Respecting Technique on the Deformity of Limb Alignment in Japanese Patients
title_sort effects of unrestricted kinematically aligned total knee arthroplasty with a modified soft tissue respecting technique on the deformity of limb alignment in japanese patients
topic total knee arthroplasty
unrestricted kinematically aligned TKA
kinematic alignment
soft-tissue respecting technique
url https://www.mdpi.com/1648-9144/59/11/1969
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