Three-dimensional culture and clinical drug responses of a highly metastatic human ovarian cancer HO-8910PM cells in nanofibrous microenvironments of three hydrogel biomaterials

Three-dimensional culture and clinical drug responses of a highly metastatic human ovarian cancer HO-8910PM cells in nanofibrous microenvironments of three hydrogel biomaterials

Abstract Background Ovarian cancer is a highly aggressive malignant disease in gynecologic cancer. It is an urgent task to develop three-dimensional (3D) cell models in vitro and dissect the cell progression-related drug resistance mechanisms in vivo. In the present study, RADA16-I peptide has the r...

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Bibliographic Details
Main Authors: Hong Song, Guo-hui Cai, Jian Liang, Di-shu Ao, Huan Wang, Ze-hong Yang
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Journal of Nanobiotechnology
Subjects:
Nanofiber
Hydrogel
3D cell culture
HO-8910PM cells
Chemosensitivity
Cell growth pattern
Online Access:http://link.springer.com/article/10.1186/s12951-020-00646-x

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http://link.springer.com/article/10.1186/s12951-020-00646-x

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