Decorin promotes robust axon growth on inhibitory CSPGs and myelin via a direct effect on neurons

Decorin promotes robust axon growth on inhibitory CSPGs and myelin via a direct effect on neurons

Inhibitory chondroitin sulfate proteoglycans (CSPGs) and myelin-associated molecules are major impediments to axon regeneration within the adult central nervous system (CNS). Decorin infusion can however suppress the levels of multiple inhibitory CSPGs and promote axon growth across spinal cord inju...

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Bibliographic Details
Main Authors: Kenneth Minor, Xiufeng Tang, Genevieve Kahrilas, Simon J. Archibald, Jeannette E. Davies, Stephen J. Davies
Format: Article
Language:English
Published: Elsevier 2008-10-01
Series:Neurobiology of Disease
Subjects:
Decorin
Chondroitin surfate proteoglycans
Myelin associated inhibitors
Mag
NOGO-A
OMgp
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108001344

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