From stillness to motion: 80 years after the first description of Taenia solium oncosphere hatching
Abstract Background Human neurocysticercosis (NCC) is a considered public health problem in many underdeveloped and developing countries. Because of the enormous increase in international tourism and migration, NCC nowadays is also found in some developed countries. Our group was the first to demons...
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| Format: | Article |
| Language: | English |
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BMC
2014-01-01
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| Series: | Parasites & Vectors |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/1756-3305-7-12 |
| _version_ | 1797811696856727552 |
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| author | Fela Mendlovic Adriana Garza-Rodríguez Joaquin Carrillo-Farga Fernando González-Domínguez Pablo Maravilla Ana Flisser |
| author_facet | Fela Mendlovic Adriana Garza-Rodríguez Joaquin Carrillo-Farga Fernando González-Domínguez Pablo Maravilla Ana Flisser |
| author_sort | Fela Mendlovic |
| collection | DOAJ |
| description | Abstract Background Human neurocysticercosis (NCC) is a considered public health problem in many underdeveloped and developing countries. Because of the enormous increase in international tourism and migration, NCC nowadays is also found in some developed countries. Our group was the first to demonstrate that tapeworm carriers in the household are the main risk factor for acquiring cysticercosis in humans and pigs, since the disease results from the ingestion of microscopic tapeworm eggs. Findings We had the opportunity to film the liberation of the embryo from the oncospheral membrane after the hatching of the egg, which is the activation process required for intestinal wall invasion by the onchosphere. Yoshino (J Formosa Med Ass 32:139-142, 1933) described with great detail in diagrams and photographs this process eighty years ago after he infected himself with three living cysticerci in order to study the life cycle of Taenia solium. Other authors further described this process. Nevertheless it has never been filmed before. The purpose of this paper is to shift from stillness to motion since we can now show for the first time a movie of an activated oncosphere and its release from the oncospheral membrane. Conclusion Oncospheral activation is the requisite for T. solium embryos to invade the intestinal mucosa and develop into cysticerci. This process has been amply described but here it is shown for the first time in motion; thus it may be of interest for readers of the journal and useful for educational purposes towards the control of NCC. |
| first_indexed | 2024-03-13T07:27:33Z |
| format | Article |
| id | doaj.art-920cb0c92b73487482ab213c9c4952ba |
| institution | Directory Open Access Journal |
| issn | 1756-3305 |
| language | English |
| last_indexed | 2024-03-13T07:27:33Z |
| publishDate | 2014-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Parasites & Vectors |
| spelling | doaj.art-920cb0c92b73487482ab213c9c4952ba2023-06-04T11:17:33ZengBMCParasites & Vectors1756-33052014-01-01711310.1186/1756-3305-7-12From stillness to motion: 80 years after the first description of Taenia solium oncosphere hatchingFela Mendlovic0Adriana Garza-Rodríguez1Joaquin Carrillo-Farga2Fernando González-Domínguez3Pablo Maravilla4Ana Flisser5Facultad de Medicina, Universidad Nacional Autónoma de MéxicoDirección de Investigación, Hospital General “Dr. Manuel Gea González” SSAInstituto de HematopatologíaDirección de Investigación, Hospital General “Dr. Manuel Gea González” SSADirección de Investigación, Hospital General “Dr. Manuel Gea González” SSAFacultad de Medicina, Universidad Nacional Autónoma de MéxicoAbstract Background Human neurocysticercosis (NCC) is a considered public health problem in many underdeveloped and developing countries. Because of the enormous increase in international tourism and migration, NCC nowadays is also found in some developed countries. Our group was the first to demonstrate that tapeworm carriers in the household are the main risk factor for acquiring cysticercosis in humans and pigs, since the disease results from the ingestion of microscopic tapeworm eggs. Findings We had the opportunity to film the liberation of the embryo from the oncospheral membrane after the hatching of the egg, which is the activation process required for intestinal wall invasion by the onchosphere. Yoshino (J Formosa Med Ass 32:139-142, 1933) described with great detail in diagrams and photographs this process eighty years ago after he infected himself with three living cysticerci in order to study the life cycle of Taenia solium. Other authors further described this process. Nevertheless it has never been filmed before. The purpose of this paper is to shift from stillness to motion since we can now show for the first time a movie of an activated oncosphere and its release from the oncospheral membrane. Conclusion Oncospheral activation is the requisite for T. solium embryos to invade the intestinal mucosa and develop into cysticerci. This process has been amply described but here it is shown for the first time in motion; thus it may be of interest for readers of the journal and useful for educational purposes towards the control of NCC.https://doi.org/10.1186/1756-3305-7-12ActivationCysticercosisHatchingHumansNeurocysticercosisOncospheres |
| spellingShingle | Fela Mendlovic Adriana Garza-Rodríguez Joaquin Carrillo-Farga Fernando González-Domínguez Pablo Maravilla Ana Flisser From stillness to motion: 80 years after the first description of Taenia solium oncosphere hatching Parasites & Vectors Activation Cysticercosis Hatching Humans Neurocysticercosis Oncospheres |
| title | From stillness to motion: 80 years after the first description of Taenia solium oncosphere hatching |
| title_full | From stillness to motion: 80 years after the first description of Taenia solium oncosphere hatching |
| title_fullStr | From stillness to motion: 80 years after the first description of Taenia solium oncosphere hatching |
| title_full_unstemmed | From stillness to motion: 80 years after the first description of Taenia solium oncosphere hatching |
| title_short | From stillness to motion: 80 years after the first description of Taenia solium oncosphere hatching |
| title_sort | from stillness to motion 80 years after the first description of taenia solium oncosphere hatching |
| topic | Activation Cysticercosis Hatching Humans Neurocysticercosis Oncospheres |
| url | https://doi.org/10.1186/1756-3305-7-12 |
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