A Reversibly Responsive Fluorochromic Hydrogel Based on Lanthanide–Mannose Complex
Abstract Fluorochromic materials that are dynamic in response to external stimuli are of great interest for the development of advanced sensors and luminescent materials. Herein, a design based on a lanthanide‐containing polymeric hydrogel possessing characteristic emission of lanthanides (Eu and Tb...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-05-01
|
| Series: | Advanced Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/advs.201802112 |
| _version_ | 1819152246311485440 |
|---|---|
| author | Ke Meng Chi Yao Qianmin Ma Zhaohui Xue Yaping Du Wenguang Liu Dayong Yang |
| author_facet | Ke Meng Chi Yao Qianmin Ma Zhaohui Xue Yaping Du Wenguang Liu Dayong Yang |
| author_sort | Ke Meng |
| collection | DOAJ |
| description | Abstract Fluorochromic materials that are dynamic in response to external stimuli are of great interest for the development of advanced sensors and luminescent materials. Herein, a design based on a lanthanide‐containing polymeric hydrogel possessing characteristic emission of lanthanides (Eu and Tb) and showing response to stimuli of metal ions is reported. The fluorochromic hydrogel is prepared using a lanthanide–mannose complex in gelation matrix. The lanthanide–mannose complex shows tunable fluorescent emission in response to Fe2+, due to the inhibition of the “antenna effect” between metal ions and ligands upon stimulation. The fluorescent hydrogel shows reversible “On/Off” fluorochromic response to Fe2+/ethylenediaminetetraacetic acid (EDTA). Remarkably, the fluorescent hydrogel is proven nontoxic and biocompatible; and a proof‐of‐application as in situ 3D cell culture extracellular matrix with reversible fluorochromic “On/Off” switch upon Fe2+/EDTA is demonstrated. This reversibly responsive fluorochromic hydrogel demonstrates a way to fabricate smart optical materials, particularly for biological‐related applications where reversible response is required. |
| first_indexed | 2024-12-22T14:46:14Z |
| format | Article |
| id | doaj.art-92115d25f42441dd92215d763e521282 |
| institution | Directory Open Access Journal |
| issn | 2198-3844 |
| language | English |
| last_indexed | 2024-12-22T14:46:14Z |
| publishDate | 2019-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | Advanced Science |
| spelling | doaj.art-92115d25f42441dd92215d763e5212822022-12-21T18:22:26ZengWileyAdvanced Science2198-38442019-05-01610n/an/a10.1002/advs.201802112A Reversibly Responsive Fluorochromic Hydrogel Based on Lanthanide–Mannose ComplexKe Meng0Chi Yao1Qianmin Ma2Zhaohui Xue3Yaping Du4Wenguang Liu5Dayong Yang6Frontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (MOE) School of Chemical Engineering and Technology Tianjin University Tianjin 300350 P. R. ChinaFrontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (MOE) School of Chemical Engineering and Technology Tianjin University Tianjin 300350 P. R. ChinaFrontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (MOE) School of Chemical Engineering and Technology Tianjin University Tianjin 300350 P. R. ChinaFrontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (MOE) School of Chemical Engineering and Technology Tianjin University Tianjin 300350 P. R. ChinaSchool of Materials Science and Engineering & National Institute for Advanced Materials Center for Rare Earth and Inorganic Functional Materials Nankai University Tianjin 300350 P. R. ChinaSchool of Materials Science and Engineering Tianjin Key Laboratory of Composite and Functional Materials Tianjin University Tianjin 300350 P. R. ChinaFrontier Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (MOE) School of Chemical Engineering and Technology Tianjin University Tianjin 300350 P. R. ChinaAbstract Fluorochromic materials that are dynamic in response to external stimuli are of great interest for the development of advanced sensors and luminescent materials. Herein, a design based on a lanthanide‐containing polymeric hydrogel possessing characteristic emission of lanthanides (Eu and Tb) and showing response to stimuli of metal ions is reported. The fluorochromic hydrogel is prepared using a lanthanide–mannose complex in gelation matrix. The lanthanide–mannose complex shows tunable fluorescent emission in response to Fe2+, due to the inhibition of the “antenna effect” between metal ions and ligands upon stimulation. The fluorescent hydrogel shows reversible “On/Off” fluorochromic response to Fe2+/ethylenediaminetetraacetic acid (EDTA). Remarkably, the fluorescent hydrogel is proven nontoxic and biocompatible; and a proof‐of‐application as in situ 3D cell culture extracellular matrix with reversible fluorochromic “On/Off” switch upon Fe2+/EDTA is demonstrated. This reversibly responsive fluorochromic hydrogel demonstrates a way to fabricate smart optical materials, particularly for biological‐related applications where reversible response is required.https://doi.org/10.1002/advs.2018021123D cell culturefluorochromic materialshydrogelslanthanide–mannose complexresponsive materials |
| spellingShingle | Ke Meng Chi Yao Qianmin Ma Zhaohui Xue Yaping Du Wenguang Liu Dayong Yang A Reversibly Responsive Fluorochromic Hydrogel Based on Lanthanide–Mannose Complex Advanced Science 3D cell culture fluorochromic materials hydrogels lanthanide–mannose complex responsive materials |
| title | A Reversibly Responsive Fluorochromic Hydrogel Based on Lanthanide–Mannose Complex |
| title_full | A Reversibly Responsive Fluorochromic Hydrogel Based on Lanthanide–Mannose Complex |
| title_fullStr | A Reversibly Responsive Fluorochromic Hydrogel Based on Lanthanide–Mannose Complex |
| title_full_unstemmed | A Reversibly Responsive Fluorochromic Hydrogel Based on Lanthanide–Mannose Complex |
| title_short | A Reversibly Responsive Fluorochromic Hydrogel Based on Lanthanide–Mannose Complex |
| title_sort | reversibly responsive fluorochromic hydrogel based on lanthanide mannose complex |
| topic | 3D cell culture fluorochromic materials hydrogels lanthanide–mannose complex responsive materials |
| url | https://doi.org/10.1002/advs.201802112 |
| work_keys_str_mv | AT kemeng areversiblyresponsivefluorochromichydrogelbasedonlanthanidemannosecomplex AT chiyao areversiblyresponsivefluorochromichydrogelbasedonlanthanidemannosecomplex AT qianminma areversiblyresponsivefluorochromichydrogelbasedonlanthanidemannosecomplex AT zhaohuixue areversiblyresponsivefluorochromichydrogelbasedonlanthanidemannosecomplex AT yapingdu areversiblyresponsivefluorochromichydrogelbasedonlanthanidemannosecomplex AT wenguangliu areversiblyresponsivefluorochromichydrogelbasedonlanthanidemannosecomplex AT dayongyang areversiblyresponsivefluorochromichydrogelbasedonlanthanidemannosecomplex AT kemeng reversiblyresponsivefluorochromichydrogelbasedonlanthanidemannosecomplex AT chiyao reversiblyresponsivefluorochromichydrogelbasedonlanthanidemannosecomplex AT qianminma reversiblyresponsivefluorochromichydrogelbasedonlanthanidemannosecomplex AT zhaohuixue reversiblyresponsivefluorochromichydrogelbasedonlanthanidemannosecomplex AT yapingdu reversiblyresponsivefluorochromichydrogelbasedonlanthanidemannosecomplex AT wenguangliu reversiblyresponsivefluorochromichydrogelbasedonlanthanidemannosecomplex AT dayongyang reversiblyresponsivefluorochromichydrogelbasedonlanthanidemannosecomplex |