Ancient DNA of the Don-Hares Assumes the Existence of Two Distinct Mitochondrial Clades in Northeast Asia
Paleoclimatic changes during the Pleistocene–Holocene transition is suggested as a main factor that led to species extinction, including the woolly mammoth (<i>Mammuthus primigenius</i>), Steller’s sea cow (<i>Hydrodamalis gigas</i>) and the Don-hare (<i>Lepus tanaiticu...
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| Format: | Article |
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MDPI AG
2023-03-01
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| Series: | Genes |
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| Online Access: | https://www.mdpi.com/2073-4425/14/3/700 |
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| author | Fedor Sharko Natalia Slobodova Eugenia Boulygina Maksim Cheprasov Maria Gladysheva-Azgari Svetlana Tsygankova Sergey Rastorguev Gavril Novgorodov Gennady Boeskorov Lena Grigorieva Woo Suk Hwang Alexei Tikhonov Artem Nedoluzhko |
| author_facet | Fedor Sharko Natalia Slobodova Eugenia Boulygina Maksim Cheprasov Maria Gladysheva-Azgari Svetlana Tsygankova Sergey Rastorguev Gavril Novgorodov Gennady Boeskorov Lena Grigorieva Woo Suk Hwang Alexei Tikhonov Artem Nedoluzhko |
| author_sort | Fedor Sharko |
| collection | DOAJ |
| description | Paleoclimatic changes during the Pleistocene–Holocene transition is suggested as a main factor that led to species extinction, including the woolly mammoth (<i>Mammuthus primigenius</i>), Steller’s sea cow (<i>Hydrodamalis gigas</i>) and the Don-hare (<i>Lepus tanaiticus</i>). These species inhabited the territory of Eurasia during the Holocene, but eventually went extinct. The Don-hare is an extinct species of the genus <i>Lepus</i> (Leporidae, Lagomorpha), which lived in the Late Pleistocene–Early Holocene in Eastern Europe and Northern Asia. For a long time, the Don-hare was considered a separate species, but at the same time, its species status was disputed, taking into account both morphological data and mitochondrial DNA. In this study, mitochondrial genomes of five Don-hares, whose remains were found on the territory of Northeastern Eurasia were reconstructed. Firstly, we confirm the phylogenetic proximity of the “young” specimens of Don-hare and mountain or white hare, and secondly, that samples older than 39 Kya form a completely distinct mitochondrial clade. |
| first_indexed | 2024-03-11T06:30:11Z |
| format | Article |
| id | doaj.art-9212cdcd768f460380cc24654206f491 |
| institution | Directory Open Access Journal |
| issn | 2073-4425 |
| language | English |
| last_indexed | 2024-03-11T06:30:11Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Genes |
| spelling | doaj.art-9212cdcd768f460380cc24654206f4912023-11-17T11:18:14ZengMDPI AGGenes2073-44252023-03-0114370010.3390/genes14030700Ancient DNA of the Don-Hares Assumes the Existence of Two Distinct Mitochondrial Clades in Northeast AsiaFedor Sharko0Natalia Slobodova1Eugenia Boulygina2Maksim Cheprasov3Maria Gladysheva-Azgari4Svetlana Tsygankova5Sergey Rastorguev6Gavril Novgorodov7Gennady Boeskorov8Lena Grigorieva9Woo Suk Hwang10Alexei Tikhonov11Artem Nedoluzhko12Research Center of Biotechnology of the Russian Academy of Sciences, 119071 Moscow, RussiaKurchatov Center for Genomic Research, National Research Centre “Kurchatov Institute”, 123182 Moscow, RussiaKurchatov Center for Genomic Research, National Research Centre “Kurchatov Institute”, 123182 Moscow, RussiaLazarev Mammoth Museum, M.K. Ammosov North-Eastern Federal University, 677000 Yakutsk, RussiaKurchatov Center for Genomic Research, National Research Centre “Kurchatov Institute”, 123182 Moscow, RussiaKurchatov Center for Genomic Research, National Research Centre “Kurchatov Institute”, 123182 Moscow, RussiaLaboratory of Experimental Embryology, Institute of Translational Medicine, Pirogov Russian National Research Medical University, 117997 Moscow, RussiaLazarev Mammoth Museum, M.K. Ammosov North-Eastern Federal University, 677000 Yakutsk, RussiaInstitute of Diamond and Precious Metals Geology, Siberian Branch of the Russian Academy of Sciences, 677007 Yakutsk, RussiaCenter of Molecular Paleontology, M.K. Ammosov North-Eastern Federal University, 677000 Yakutsk, RussiaUAE Biotech Research Center, Abu Dhabi 30310, United Arab EmiratesLazarev Mammoth Museum, M.K. Ammosov North-Eastern Federal University, 677000 Yakutsk, RussiaPaleogenomics Laboratory, European University at Saint Petersburg, 191187 Saint Petersburg, RussiaPaleoclimatic changes during the Pleistocene–Holocene transition is suggested as a main factor that led to species extinction, including the woolly mammoth (<i>Mammuthus primigenius</i>), Steller’s sea cow (<i>Hydrodamalis gigas</i>) and the Don-hare (<i>Lepus tanaiticus</i>). These species inhabited the territory of Eurasia during the Holocene, but eventually went extinct. The Don-hare is an extinct species of the genus <i>Lepus</i> (Leporidae, Lagomorpha), which lived in the Late Pleistocene–Early Holocene in Eastern Europe and Northern Asia. For a long time, the Don-hare was considered a separate species, but at the same time, its species status was disputed, taking into account both morphological data and mitochondrial DNA. In this study, mitochondrial genomes of five Don-hares, whose remains were found on the territory of Northeastern Eurasia were reconstructed. Firstly, we confirm the phylogenetic proximity of the “young” specimens of Don-hare and mountain or white hare, and secondly, that samples older than 39 Kya form a completely distinct mitochondrial clade.https://www.mdpi.com/2073-4425/14/3/700Don-hare<i>L. tanaiticus</i>mountain hare<i>L. timidus</i>Holoceneancient DNA |
| spellingShingle | Fedor Sharko Natalia Slobodova Eugenia Boulygina Maksim Cheprasov Maria Gladysheva-Azgari Svetlana Tsygankova Sergey Rastorguev Gavril Novgorodov Gennady Boeskorov Lena Grigorieva Woo Suk Hwang Alexei Tikhonov Artem Nedoluzhko Ancient DNA of the Don-Hares Assumes the Existence of Two Distinct Mitochondrial Clades in Northeast Asia Genes Don-hare <i>L. tanaiticus</i> mountain hare <i>L. timidus</i> Holocene ancient DNA |
| title | Ancient DNA of the Don-Hares Assumes the Existence of Two Distinct Mitochondrial Clades in Northeast Asia |
| title_full | Ancient DNA of the Don-Hares Assumes the Existence of Two Distinct Mitochondrial Clades in Northeast Asia |
| title_fullStr | Ancient DNA of the Don-Hares Assumes the Existence of Two Distinct Mitochondrial Clades in Northeast Asia |
| title_full_unstemmed | Ancient DNA of the Don-Hares Assumes the Existence of Two Distinct Mitochondrial Clades in Northeast Asia |
| title_short | Ancient DNA of the Don-Hares Assumes the Existence of Two Distinct Mitochondrial Clades in Northeast Asia |
| title_sort | ancient dna of the don hares assumes the existence of two distinct mitochondrial clades in northeast asia |
| topic | Don-hare <i>L. tanaiticus</i> mountain hare <i>L. timidus</i> Holocene ancient DNA |
| url | https://www.mdpi.com/2073-4425/14/3/700 |
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