Fabrication of TPGS decorated Etravirine loaded lipidic nanocarriers as a neoteric oral bioavailability enhancer for lymphatic targeting

Fabrication of TPGS decorated Etravirine loaded lipidic nanocarriers as a neoteric oral bioavailability enhancer for lymphatic targeting

Abstract Etravirine (ERVN) is a potential NNRTI (non-nucleoside reverse transcriptase inhibitor) in treating HIV infection. It possesses extremely low oral bioavailability. The present research aims to optimize the formulation and characterization of TPGS-enriched ERVN-loaded lipid-based nanocarrier...

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Bibliographic Details
Main Authors: Abdul Muheem, Mohd. Wasim, Eman Aldosari, Sanjula Baboota, Javed Ali
Format: Article
Language:English
Published: Springer 2024-01-01
Series:Discover Nano
Subjects:
Lipidic nanocarriers
NLCs
TPGS
Etravirine
HIV
AIDS
Online Access:https://doi.org/10.1186/s11671-023-03954-x

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