Design of 1-(furan-2-yl)-N-(5-substituted phenyl-1, 3, 4-thiadiazol-2-yl) methanimine derivatives as Enoyl-ACP reductase inhibitors: Synthesis, molecular docking studies and antitubercular activity

Design of 1-(furan-2-yl)-N-(5-substituted phenyl-1, 3, 4-thiadiazol-2-yl) methanimine derivatives as Enoyl-ACP reductase inhibitors: Synthesis, molecular docking studies and antitubercular activity

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A series of 5-phenylsubstiuted 1, 3, 4 thiadiazoles clubbed with furan moiety (Fa-Fe) by means of azomethine linkage have been synthesized. All the newly synthesized compounds were characterized by IR,1HNMR and Mass analyses. All the synthesized molecules have been predicted as antitubercular in nat...

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Bibliographic Details
Main Authors:	Bijo Mathew, Githa Elizabeth Mathew, George Sonia, Anila Kumar, Neethu P Charles, Palanisamy Kumar
Format:	Article
Language:	English
Published:	Bangladesh Pharmacological Society 2013-05-01
Series:	Bangladesh Journal of Pharmacology
Subjects:	KeEnol-ACP reductase Molecular docking 1 3 4-thiadiazole
Online Access:	https://www.banglajol.info/index.php/BJP/article/view/14778

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