The AFF-1 exoplasmic fusogen is required for endocytic scission and seamless tube elongation
Membrane fusion and fission events at exoplasmic membrane surfaces are not well understood. Here the authors show that the C. elegans cell–cell fusogen AFF-1 is required for endocytic scission and apically-directed membrane trafficking during the development of a unicellular tube.
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2018-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-04091-1 |
| _version_ | 1818341818160381952 |
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| author | Fabien Soulavie David H. Hall Meera V. Sundaram |
| author_facet | Fabien Soulavie David H. Hall Meera V. Sundaram |
| author_sort | Fabien Soulavie |
| collection | DOAJ |
| description | Membrane fusion and fission events at exoplasmic membrane surfaces are not well understood. Here the authors show that the C. elegans cell–cell fusogen AFF-1 is required for endocytic scission and apically-directed membrane trafficking during the development of a unicellular tube. |
| first_indexed | 2024-12-13T16:04:50Z |
| format | Article |
| id | doaj.art-921eae60eb714bf09a1d1df17930155c |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-13T16:04:50Z |
| publishDate | 2018-05-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-921eae60eb714bf09a1d1df17930155c2022-12-21T23:39:05ZengNature PortfolioNature Communications2041-17232018-05-019111110.1038/s41467-018-04091-1The AFF-1 exoplasmic fusogen is required for endocytic scission and seamless tube elongationFabien Soulavie0David H. Hall1Meera V. Sundaram2Department of Genetics, University of Pennsylvania Perelman School of MedicineDepartment of Neuroscience, Albert Einstein College of MedicineDepartment of Genetics, University of Pennsylvania Perelman School of MedicineMembrane fusion and fission events at exoplasmic membrane surfaces are not well understood. Here the authors show that the C. elegans cell–cell fusogen AFF-1 is required for endocytic scission and apically-directed membrane trafficking during the development of a unicellular tube.https://doi.org/10.1038/s41467-018-04091-1 |
| spellingShingle | Fabien Soulavie David H. Hall Meera V. Sundaram The AFF-1 exoplasmic fusogen is required for endocytic scission and seamless tube elongation Nature Communications |
| title | The AFF-1 exoplasmic fusogen is required for endocytic scission and seamless tube elongation |
| title_full | The AFF-1 exoplasmic fusogen is required for endocytic scission and seamless tube elongation |
| title_fullStr | The AFF-1 exoplasmic fusogen is required for endocytic scission and seamless tube elongation |
| title_full_unstemmed | The AFF-1 exoplasmic fusogen is required for endocytic scission and seamless tube elongation |
| title_short | The AFF-1 exoplasmic fusogen is required for endocytic scission and seamless tube elongation |
| title_sort | aff 1 exoplasmic fusogen is required for endocytic scission and seamless tube elongation |
| url | https://doi.org/10.1038/s41467-018-04091-1 |
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