Multimodal Integrative Genomics and Pathology Analyses in Neoadjuvant Nivolumab Treatment for Intermediate and Locally Advanced Hepatocellular Carcinoma

Multimodal Integrative Genomics and Pathology Analyses in Neoadjuvant Nivolumab Treatment for Intermediate and Locally Advanced Hepatocellular Carcinoma

Introduction: Immunotherapy has resulted in pathologic responses in hepatocellular carcinoma (HCC), but the benefits and molecular mechanisms of neoadjuvant immune checkpoint blockade are largely unknown. Methods: In this study, we evaluated the efficacy and safety of preoperative nivolumab (anti-PD...

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Main Authors: Tan-To Cheung, Daniel Wai-Hung Ho, Shirley Xueying Lyu, Qingyang Zhang, Yu-Man Tsui, Tiffany Ching-Yun Yu, Karen Man-Fong Sze, Joyce Man-Fong Lee, Vince Wing-hang Lau, Edward Yin-Lun Chu, Simon Hing-Yin Tsang, Wong-Hoi She, Roland Ching-Yu Leung, Thomas Chung-Cheung Yau, Irene Oi-Lin Ng
Format: Article
Language:English
Published: Karger Publishers 2023-05-01
Series:Liver Cancer
Subjects:
anti-pd-1
preoperative nivolumab
resection
multiomics
Online Access:https://beta.karger.com/Article/FullText/531176

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