MYC: a multipurpose oncogene with prognostic and therapeutic implications in blood malignancies

MYC: a multipurpose oncogene with prognostic and therapeutic implications in blood malignancies

Abstract MYC oncogene is a transcription factor with a wide array of functions affecting cellular activities such as cell cycle, apoptosis, DNA damage response, and hematopoiesis. Due to the multi-functionality of MYC, its expression is regulated at multiple levels. Deregulation of this oncogene can...

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Bibliographic Details
Main Authors: Seyed Esmaeil Ahmadi, Samira Rahimi, Bahman Zarandi, Rouzbeh Chegeni, Majid Safa
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Journal of Hematology & Oncology
Subjects:
MYC
Oncogene
Regulation
Cell cycle
Apoptosis
DNA damage response
Online Access:https://doi.org/10.1186/s13045-021-01111-4

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