DNA Methylation Biomarkers for Prediction of Response to Platinum-Based Chemotherapy: Where Do We Stand?

DNA Methylation Biomarkers for Prediction of Response to Platinum-Based Chemotherapy: Where Do We Stand?

Platinum-based chemotherapy is routinely used for the treatment of several cancers. Despite all the advances made in cancer research regarding this therapy and its mechanisms of action, tumor resistance remains a major concern, limiting its effectiveness. DNA methylation-based biomarkers may assist...

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Bibliographic Details
Main Authors: Nuno Tiago Tavares, Saulė Gumauskaitė, João Lobo, Carmen Jerónimo, Rui Henrique
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Cancers
Subjects:
cancer
platinum-based chemotherapy
epigenetics
DNA methylation
biomarker
Online Access:https://www.mdpi.com/2072-6694/14/12/2918

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