Nonhomologous Recombination between Defective Poliovirus and Coxsackievirus Genomes Suggests a New Model of Genetic Plasticity for Picornaviruses

Nonhomologous Recombination between Defective Poliovirus and Coxsackievirus Genomes Suggests a New Model of Genetic Plasticity for Picornaviruses

ABSTRACT Most of the circulating vaccine-derived polioviruses (cVDPVs) implicated in poliomyelitis outbreaks in Madagascar have been shown to be recombinants between the type 2 poliovirus (PV) strain of the oral polio vaccine (Sabin 2) and another species C human enterovirus (HEV-C), such as type 17...

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Bibliographic Details
Main Authors: Barbara Holmblat, Sophie Jégouic, Claire Muslin, Bruno Blondel, Marie-Line Joffret, Francis Delpeyroux
Format: Article
Language:English
Published: American Society for Microbiology 2014-08-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.01119-14

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