Autoimmune Hepatitis and Systemic Sclerosis: a Rare Association
A woman in her early 40s, with a history of excessive alcohol intake, presented with purpuric, ulcerative lesions on the lower limbs. On examination, hirsutism and generalized stiffening and thickening of the skin were noted. Laboratory investigations revealed hyperbilirubinemia, hypergammaglobuline...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SMC MEDIA SRL
2019-12-01
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| Series: | European Journal of Case Reports in Internal Medicine |
| Subjects: | |
| Online Access: | https://www.ejcrim.com/index.php/EJCRIM/article/view/1352 |
| _version_ | 1818191384615583744 |
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| author | Elisabete Pereira Coelho Ana Rita Matos Sofia Caridade |
| author_facet | Elisabete Pereira Coelho Ana Rita Matos Sofia Caridade |
| author_sort | Elisabete Pereira Coelho |
| collection | DOAJ |
| description | A woman in her early 40s, with a history of excessive alcohol intake, presented with purpuric, ulcerative lesions on the lower limbs. On examination, hirsutism and generalized stiffening and thickening of the skin were noted. Laboratory investigations revealed hyperbilirubinemia, hypergammaglobulinemia and positive anti-smooth muscle antibodies. Histologic examination of the skin was compatible with scleroderma. Histologic examination of the liver was suggestive of autoimmune and alcoholic hepatitis. |
| first_indexed | 2024-12-12T00:13:45Z |
| format | Article |
| id | doaj.art-922ce329683c46fda1c5a465c7ac2181 |
| institution | Directory Open Access Journal |
| issn | 2284-2594 |
| language | English |
| last_indexed | 2024-12-12T00:13:45Z |
| publishDate | 2019-12-01 |
| publisher | SMC MEDIA SRL |
| record_format | Article |
| series | European Journal of Case Reports in Internal Medicine |
| spelling | doaj.art-922ce329683c46fda1c5a465c7ac21812022-12-22T00:44:54ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942019-12-0110.12890/2019_0013521352Autoimmune Hepatitis and Systemic Sclerosis: a Rare AssociationElisabete Pereira Coelho0Ana Rita Matos1Sofia Caridade2Unidade de Cuidados Intensivos Polivalente, Hospital de Braga, Braga, PortugalServiço de Medicina Interna, Hospital de Braga, Braga, PortugalServiço de Medicina Interna, Hospital de Braga, Braga, PortugalA woman in her early 40s, with a history of excessive alcohol intake, presented with purpuric, ulcerative lesions on the lower limbs. On examination, hirsutism and generalized stiffening and thickening of the skin were noted. Laboratory investigations revealed hyperbilirubinemia, hypergammaglobulinemia and positive anti-smooth muscle antibodies. Histologic examination of the skin was compatible with scleroderma. Histologic examination of the liver was suggestive of autoimmune and alcoholic hepatitis.https://www.ejcrim.com/index.php/EJCRIM/article/view/1352autoimmune hepatitissystemic sclerosisalcoholic hepatitis |
| spellingShingle | Elisabete Pereira Coelho Ana Rita Matos Sofia Caridade Autoimmune Hepatitis and Systemic Sclerosis: a Rare Association European Journal of Case Reports in Internal Medicine autoimmune hepatitis systemic sclerosis alcoholic hepatitis |
| title | Autoimmune Hepatitis and Systemic Sclerosis: a Rare Association |
| title_full | Autoimmune Hepatitis and Systemic Sclerosis: a Rare Association |
| title_fullStr | Autoimmune Hepatitis and Systemic Sclerosis: a Rare Association |
| title_full_unstemmed | Autoimmune Hepatitis and Systemic Sclerosis: a Rare Association |
| title_short | Autoimmune Hepatitis and Systemic Sclerosis: a Rare Association |
| title_sort | autoimmune hepatitis and systemic sclerosis a rare association |
| topic | autoimmune hepatitis systemic sclerosis alcoholic hepatitis |
| url | https://www.ejcrim.com/index.php/EJCRIM/article/view/1352 |
| work_keys_str_mv | AT elisabetepereiracoelho autoimmunehepatitisandsystemicsclerosisarareassociation AT anaritamatos autoimmunehepatitisandsystemicsclerosisarareassociation AT sofiacaridade autoimmunehepatitisandsystemicsclerosisarareassociation |