Evaluation of human milk titratable acidity before and after addition of a nutritional supplement for preterm newborns

Objective: To evaluate the initial Dornic acidity in raw human milk, after pasteurization and after heating and dilution of a dietary supplement for preterm infants. Methods: A quantitative, descriptive, and experimental study was carried out with a convenience sample at the human milk bank at a Bra...

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Main Authors: Cibelle Iáskara do Vale Pereira, Juliana Fernandes dos Santos Dametto, Janaína Cavalcanti Costa Oliveira
Format: Article
Language:Portuguese
Published: Brazilian Society of Pediatrics 2016-09-01
Series:Jornal de Pediatria (Versão em Português)
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2255553616300775
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author Cibelle Iáskara do Vale Pereira
Juliana Fernandes dos Santos Dametto
Janaína Cavalcanti Costa Oliveira
author_facet Cibelle Iáskara do Vale Pereira
Juliana Fernandes dos Santos Dametto
Janaína Cavalcanti Costa Oliveira
author_sort Cibelle Iáskara do Vale Pereira
collection DOAJ
description Objective: To evaluate the initial Dornic acidity in raw human milk, after pasteurization and after heating and dilution of a dietary supplement for preterm infants. Methods: A quantitative, descriptive, and experimental study was carried out with a convenience sample at the human milk bank at a Brazilian public maternity, with specialized care for pregnant women and newborns at risk. The eligibility criteria for the study sample included 93 frozen raw human milk in suitable containers with volumes ≥100 mL and initial Dornic acidity ≤8° Dornic (° D). Milk acidity of human milk was measured in four stages: in raw human milk (initial); after pasteurization; after the heating of pasteurized milk and dilution of the supplement; and after thirty minutes of supplementation. Results: The initial acidity was 3.8° D ± 1.3 (95% CI: 3.56–4.09) with no significant difference in Dornic acidity in pasteurized milk, which was 3.6° D ± 1.2 (95% CI: 3.36–3.87). The dilution of the supplement in pasteurized milk that was heated significantly increased mean Dornic acidity to 18.6 °D ± 2.2 (95% CI: 18.18–19.11), which remained high after thirty minutes of supplementation at 17.8 °D ± 2.2 (95% CI: 17.36–18.27), considering p < 0.05. Conclusions: The study observed no significant differences in Dornic acidity of raw human milk and pasteurized human milk; however, the dilution of a human milk supplementation caused a significant increase in acidity. Further investigations are necessary on the influence of this finding on the quality of supplemented milk and its consequences on the health of preterm infants.
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spelling doaj.art-922f1229ee074053a93c283f71d7b6322022-12-22T03:23:29ZporBrazilian Society of PediatricsJornal de Pediatria (Versão em Português)2255-55362016-09-0192549950410.1016/j.jpedp.2016.07.001Evaluation of human milk titratable acidity before and after addition of a nutritional supplement for preterm newbornsCibelle Iáskara do Vale Pereira0Juliana Fernandes dos Santos Dametto1Janaína Cavalcanti Costa Oliveira2Universidade Federal do Rio Grande do Norte (UFRN), Maternidade Escola Januário Cicco (MEJC), Natal, RN, BrasilUniversidade Federal do Rio Grande do Norte (UFRN), Natal, RN, BrasilUniversidade Federal do Rio Grande do Norte (UFRN), Maternidade Escola Januário Cicco (MEJC), Natal, RN, BrasilObjective: To evaluate the initial Dornic acidity in raw human milk, after pasteurization and after heating and dilution of a dietary supplement for preterm infants. Methods: A quantitative, descriptive, and experimental study was carried out with a convenience sample at the human milk bank at a Brazilian public maternity, with specialized care for pregnant women and newborns at risk. The eligibility criteria for the study sample included 93 frozen raw human milk in suitable containers with volumes ≥100 mL and initial Dornic acidity ≤8° Dornic (° D). Milk acidity of human milk was measured in four stages: in raw human milk (initial); after pasteurization; after the heating of pasteurized milk and dilution of the supplement; and after thirty minutes of supplementation. Results: The initial acidity was 3.8° D ± 1.3 (95% CI: 3.56–4.09) with no significant difference in Dornic acidity in pasteurized milk, which was 3.6° D ± 1.2 (95% CI: 3.36–3.87). The dilution of the supplement in pasteurized milk that was heated significantly increased mean Dornic acidity to 18.6 °D ± 2.2 (95% CI: 18.18–19.11), which remained high after thirty minutes of supplementation at 17.8 °D ± 2.2 (95% CI: 17.36–18.27), considering p < 0.05. Conclusions: The study observed no significant differences in Dornic acidity of raw human milk and pasteurized human milk; however, the dilution of a human milk supplementation caused a significant increase in acidity. Further investigations are necessary on the influence of this finding on the quality of supplemented milk and its consequences on the health of preterm infants.http://www.sciencedirect.com/science/article/pii/S2255553616300775NewbornHuman milkTitratable acidityDietary supplementsMetabolic bone diseases
spellingShingle Cibelle Iáskara do Vale Pereira
Juliana Fernandes dos Santos Dametto
Janaína Cavalcanti Costa Oliveira
Evaluation of human milk titratable acidity before and after addition of a nutritional supplement for preterm newborns
Jornal de Pediatria (Versão em Português)
Newborn
Human milk
Titratable acidity
Dietary supplements
Metabolic bone diseases
title Evaluation of human milk titratable acidity before and after addition of a nutritional supplement for preterm newborns
title_full Evaluation of human milk titratable acidity before and after addition of a nutritional supplement for preterm newborns
title_fullStr Evaluation of human milk titratable acidity before and after addition of a nutritional supplement for preterm newborns
title_full_unstemmed Evaluation of human milk titratable acidity before and after addition of a nutritional supplement for preterm newborns
title_short Evaluation of human milk titratable acidity before and after addition of a nutritional supplement for preterm newborns
title_sort evaluation of human milk titratable acidity before and after addition of a nutritional supplement for preterm newborns
topic Newborn
Human milk
Titratable acidity
Dietary supplements
Metabolic bone diseases
url http://www.sciencedirect.com/science/article/pii/S2255553616300775
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