Central exercise action increases the AMPK and mTOR response to leptin.

Central exercise action increases the AMPK and mTOR response to leptin.

AMP-activated protein kinase (AMPK) and mammalian Target of Rapamycin (mTOR) are key regulators of cellular energy balance and of the effects of leptin on food intake. Acute exercise is associated with increased sensitivity to the effects of leptin on food intake in an IL-6-dependent manner. To dete...

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Bibliographic Details
Main Authors: Eduardo R Ropelle, Maria Fernanda A Fernandes, Marcelo B S Flores, Mirian Ueno, Silvana Rocco, Rodrigo Marin, Dennys E Cintra, Lício A Velloso, Kleber G Franchini, Mario J A Saad, José B C Carvalheira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2585815?pdf=render

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