HIV-1 integrase resistance associated mutations and the use of dolutegravir in Sub-Saharan Africa: A systematic review and meta-analysis

HIV-1 integrase resistance associated mutations and the use of dolutegravir in Sub-Saharan Africa: A systematic review and meta-analysis

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As sub-Saharan Africa (SSA) countries are transitioning to dolutegravir (DTG)-based ART, baseline data are required for optimal monitoring of therapeutic response. In this frame, we sought to generate up-to-date evidence on the use of integrase-strand transfer inhibitors (INSTI) and associated drug...

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Main Authors: Ezechiel Ngoufack Jagni Semengue, Maria Mercedes Santoro, Valantine Ngum Ndze, Aude Christelle Ka’e, Bouba Yagai, Alex Durand Nka, Beatrice Dambaya, Desiré Takou, Georges Teto, Lavinia Fabeni, Vittorio Colizzi, Carlo-Federico Perno, Francesca Ceccherini-Silberstein, Joseph Fokam
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLOS Global Public Health
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10021461/?tool=EBI

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