3D printed drug loaded nanomaterials for wound healing applications
Wounds are a stern healthcare concern in the growth of chronic disease conditions as they can increase healthcare costs and complicate internal and external health. Advancements in the current and newer management systems for wound healing should be in place to counter the health burden of wounds. R...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-12-01
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| Series: | Regenerative Therapy |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352320423000822 |
| _version_ | 1827630315205558272 |
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| author | Ashagrachew Tewabe Yayehrad Ebrahim Abdella Siraj Motlalepula Matsabisa Gebremariam Birhanu |
| author_facet | Ashagrachew Tewabe Yayehrad Ebrahim Abdella Siraj Motlalepula Matsabisa Gebremariam Birhanu |
| author_sort | Ashagrachew Tewabe Yayehrad |
| collection | DOAJ |
| description | Wounds are a stern healthcare concern in the growth of chronic disease conditions as they can increase healthcare costs and complicate internal and external health. Advancements in the current and newer management systems for wound healing should be in place to counter the health burden of wounds. Researchers discovered that two-dimensional (2D) media lacks appropriate real-life detection of cellular matter as these have highly complicated and diverse structures, compositions, and interactions. Hence, innovation towards three-dimensional (3D) media is called to conquer the high-level assessment and characterization in vivo using new technologies. The application of modern wound dressings prepared from a degenerated natural tissue, biodegradable biopolymer, synthetic polymer, or a composite of these materials in wound healing is currently an area of innovation in tissue regeneration medicine. Moreover, the integration of 3D printing and nanomaterial science is a promising approach with the potential for individualized, flexible, and precise technology for wound care approaches. This review encompasses the outcomes of various investigations on recent advances in 3D-printed drug-loaded natural, synthetic, and composite nanomaterials for wound healing. The challenges associated with their fabrication, clinical application progress, and future perspectives are also addressed. |
| first_indexed | 2024-03-09T14:04:59Z |
| format | Article |
| id | doaj.art-9235ffa6c9934c4ca75bbd8bb1a6bb6a |
| institution | Directory Open Access Journal |
| issn | 2352-3204 |
| language | English |
| last_indexed | 2024-03-09T14:04:59Z |
| publishDate | 2023-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Regenerative Therapy |
| spelling | doaj.art-9235ffa6c9934c4ca75bbd8bb1a6bb6a2023-11-30T05:07:51ZengElsevierRegenerative Therapy2352-32042023-12-01243613763D printed drug loaded nanomaterials for wound healing applicationsAshagrachew Tewabe Yayehrad0Ebrahim Abdella Siraj1Motlalepula Matsabisa2Gebremariam Birhanu3Department of Pharmacy, School of Health Sciences, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia, PO Box: 79Department of Pharmacy, School of Health Sciences, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia, PO Box: 79; Department of Pharmaceutics and Social Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia, PO Box: 1176Department of Pharmacology, Faculty of Health Sciences, University of the Free State, Bloemfontein 9300, South AfricaDepartment of Pharmacology, Faculty of Health Sciences, University of the Free State, Bloemfontein 9300, South Africa; Corresponding author.Wounds are a stern healthcare concern in the growth of chronic disease conditions as they can increase healthcare costs and complicate internal and external health. Advancements in the current and newer management systems for wound healing should be in place to counter the health burden of wounds. Researchers discovered that two-dimensional (2D) media lacks appropriate real-life detection of cellular matter as these have highly complicated and diverse structures, compositions, and interactions. Hence, innovation towards three-dimensional (3D) media is called to conquer the high-level assessment and characterization in vivo using new technologies. The application of modern wound dressings prepared from a degenerated natural tissue, biodegradable biopolymer, synthetic polymer, or a composite of these materials in wound healing is currently an area of innovation in tissue regeneration medicine. Moreover, the integration of 3D printing and nanomaterial science is a promising approach with the potential for individualized, flexible, and precise technology for wound care approaches. This review encompasses the outcomes of various investigations on recent advances in 3D-printed drug-loaded natural, synthetic, and composite nanomaterials for wound healing. The challenges associated with their fabrication, clinical application progress, and future perspectives are also addressed.http://www.sciencedirect.com/science/article/pii/S23523204230008223D printingBiomaterialsNanocompositeNanomaterial scaffoldsWound healing |
| spellingShingle | Ashagrachew Tewabe Yayehrad Ebrahim Abdella Siraj Motlalepula Matsabisa Gebremariam Birhanu 3D printed drug loaded nanomaterials for wound healing applications Regenerative Therapy 3D printing Biomaterials Nanocomposite Nanomaterial scaffolds Wound healing |
| title | 3D printed drug loaded nanomaterials for wound healing applications |
| title_full | 3D printed drug loaded nanomaterials for wound healing applications |
| title_fullStr | 3D printed drug loaded nanomaterials for wound healing applications |
| title_full_unstemmed | 3D printed drug loaded nanomaterials for wound healing applications |
| title_short | 3D printed drug loaded nanomaterials for wound healing applications |
| title_sort | 3d printed drug loaded nanomaterials for wound healing applications |
| topic | 3D printing Biomaterials Nanocomposite Nanomaterial scaffolds Wound healing |
| url | http://www.sciencedirect.com/science/article/pii/S2352320423000822 |
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