A common cellular response to broad splicing perturbations is characterized by metabolic transcript downregulation driven by the Mdm2–p53 axis
Main Authors: | , |
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Format: | Article |
Language: | English |
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The Company of Biologists
2024-02-01
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Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/17/2/dmm050356 |
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author | Jade E. Varineau Eliezer Calo |
author_facet | Jade E. Varineau Eliezer Calo |
author_sort | Jade E. Varineau |
collection | DOAJ |
first_indexed | 2024-03-07T15:32:51Z |
format | Article |
id | doaj.art-923611cbf560495e901894919e97c297 |
institution | Directory Open Access Journal |
issn | 1754-8403 1754-8411 |
language | English |
last_indexed | 2024-03-07T15:32:51Z |
publishDate | 2024-02-01 |
publisher | The Company of Biologists |
record_format | Article |
series | Disease Models & Mechanisms |
spelling | doaj.art-923611cbf560495e901894919e97c2972024-03-05T14:49:16ZengThe Company of BiologistsDisease Models & Mechanisms1754-84031754-84112024-02-0117210.1242/dmm.050356050356A common cellular response to broad splicing perturbations is characterized by metabolic transcript downregulation driven by the Mdm2–p53 axisJade E. Varineau0Eliezer Calo1 Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA http://dmm.biologists.org/content/17/2/dmm050356craniofacial disorderssplicingp53 |
spellingShingle | Jade E. Varineau Eliezer Calo A common cellular response to broad splicing perturbations is characterized by metabolic transcript downregulation driven by the Mdm2–p53 axis Disease Models & Mechanisms craniofacial disorders splicing p53 |
title | A common cellular response to broad splicing perturbations is characterized by metabolic transcript downregulation driven by the Mdm2–p53 axis |
title_full | A common cellular response to broad splicing perturbations is characterized by metabolic transcript downregulation driven by the Mdm2–p53 axis |
title_fullStr | A common cellular response to broad splicing perturbations is characterized by metabolic transcript downregulation driven by the Mdm2–p53 axis |
title_full_unstemmed | A common cellular response to broad splicing perturbations is characterized by metabolic transcript downregulation driven by the Mdm2–p53 axis |
title_short | A common cellular response to broad splicing perturbations is characterized by metabolic transcript downregulation driven by the Mdm2–p53 axis |
title_sort | common cellular response to broad splicing perturbations is characterized by metabolic transcript downregulation driven by the mdm2 p53 axis |
topic | craniofacial disorders splicing p53 |
url | http://dmm.biologists.org/content/17/2/dmm050356 |
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