A common cellular response to broad splicing perturbations is characterized by metabolic transcript downregulation driven by the Mdm2–p53 axis
Main Authors: | Jade E. Varineau, Eliezer Calo |
---|---|
Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2024-02-01
|
Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/17/2/dmm050356 |
Similar Items
-
A Common Cellular Response to Broad Splicing
Perturbations
by: Varineau, Jade E.
Published: (2024) -
Splicing Modulation Results in Aberrant Isoforms and Protein Products of p53 Pathway Genes and the Sensitization of B Cells to Non-Genotoxic MDM2 Inhibition
by: Erhan Aptullahoglu, et al.
Published: (2023-01-01) -
Benzimidazoles Downregulate Mdm2 and MdmX and Activate p53 in MdmX Overexpressing Tumor Cells
by: Zuzana Mrkvová, et al.
Published: (2019-06-01) -
Zmat3 splices together p53-dependent tumor suppression
by: Kathryn T. Bieging-Rolett, et al.
Published: (2021-05-01) -
Snrpb is required in murine neural crest cells for proper splicing and craniofacial morphogenesis
by: Sabrina Shameen Alam, et al.
Published: (2022-06-01)