In vivo MRI with Concurrent Excitation and Acquisition using Automated Active Analog Cancellation
Abstract Magnetic resonance imaging (MRI) provides excellent cross-sectional images of the soft tissues in patients. Unfortunately, MRI is intrinsically slow, it exposes patients to severe acoustic noise levels, and is limited in the visualization of certain tissues such as bone. These limitations a...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2018-07-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-018-28894-w |
| _version_ | 1819200471370301440 |
|---|---|
| author | Ali Caglar Özen Ergin Atalar Jan G. Korvink Michael Bock |
| author_facet | Ali Caglar Özen Ergin Atalar Jan G. Korvink Michael Bock |
| author_sort | Ali Caglar Özen |
| collection | DOAJ |
| description | Abstract Magnetic resonance imaging (MRI) provides excellent cross-sectional images of the soft tissues in patients. Unfortunately, MRI is intrinsically slow, it exposes patients to severe acoustic noise levels, and is limited in the visualization of certain tissues such as bone. These limitations are partly caused by the timing structure of the MRI exam which first generates the MR signal by a strong radio-frequency excitation and later acquires the weak MRI signal. Concurrent excitation and acquisition (CEA) can overcome these limitations, but is extremely challenging due to the huge intensity difference between transmit and receive signal (up to 100 dB). To suppress the strong transmit signals during signal reception, a fully automated analog cancellation unit was designed. On a 3 Tesla clinical MRI system we achieved an on-resonance analog isolation of 90 dB between the transmit and receive path, so that CEA images of the head and the extremities could be acquired with an acquisition efficiency of higher than 90% at sound pressure levels close to background noise. CEA with analog cancellation might provide new opportunities for MRI in tissues with very short T2 relaxation times, and it offers a silent and time-efficient MRI acquisition. |
| first_indexed | 2024-12-23T03:32:40Z |
| format | Article |
| id | doaj.art-923d0966578544bfae5e3bcce7ddadbe |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-23T03:32:40Z |
| publishDate | 2018-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-923d0966578544bfae5e3bcce7ddadbe2022-12-21T18:01:37ZengNature PortfolioScientific Reports2045-23222018-07-018111210.1038/s41598-018-28894-wIn vivo MRI with Concurrent Excitation and Acquisition using Automated Active Analog CancellationAli Caglar Özen0Ergin Atalar1Jan G. Korvink2Michael Bock3Department of Radiology, Medical Physics, Medical Center - University of Freiburg, Faculty of Medicine, University of FreiburgDepartment of Electrical and Electronics Engineering, Bilkent UniversityInstitute of Microstructure Technology, Karlsruhe Institute of TechnologyDepartment of Radiology, Medical Physics, Medical Center - University of Freiburg, Faculty of Medicine, University of FreiburgAbstract Magnetic resonance imaging (MRI) provides excellent cross-sectional images of the soft tissues in patients. Unfortunately, MRI is intrinsically slow, it exposes patients to severe acoustic noise levels, and is limited in the visualization of certain tissues such as bone. These limitations are partly caused by the timing structure of the MRI exam which first generates the MR signal by a strong radio-frequency excitation and later acquires the weak MRI signal. Concurrent excitation and acquisition (CEA) can overcome these limitations, but is extremely challenging due to the huge intensity difference between transmit and receive signal (up to 100 dB). To suppress the strong transmit signals during signal reception, a fully automated analog cancellation unit was designed. On a 3 Tesla clinical MRI system we achieved an on-resonance analog isolation of 90 dB between the transmit and receive path, so that CEA images of the head and the extremities could be acquired with an acquisition efficiency of higher than 90% at sound pressure levels close to background noise. CEA with analog cancellation might provide new opportunities for MRI in tissues with very short T2 relaxation times, and it offers a silent and time-efficient MRI acquisition.https://doi.org/10.1038/s41598-018-28894-w |
| spellingShingle | Ali Caglar Özen Ergin Atalar Jan G. Korvink Michael Bock In vivo MRI with Concurrent Excitation and Acquisition using Automated Active Analog Cancellation Scientific Reports |
| title | In vivo MRI with Concurrent Excitation and Acquisition using Automated Active Analog Cancellation |
| title_full | In vivo MRI with Concurrent Excitation and Acquisition using Automated Active Analog Cancellation |
| title_fullStr | In vivo MRI with Concurrent Excitation and Acquisition using Automated Active Analog Cancellation |
| title_full_unstemmed | In vivo MRI with Concurrent Excitation and Acquisition using Automated Active Analog Cancellation |
| title_short | In vivo MRI with Concurrent Excitation and Acquisition using Automated Active Analog Cancellation |
| title_sort | in vivo mri with concurrent excitation and acquisition using automated active analog cancellation |
| url | https://doi.org/10.1038/s41598-018-28894-w |
| work_keys_str_mv | AT alicaglarozen invivomriwithconcurrentexcitationandacquisitionusingautomatedactiveanalogcancellation AT erginatalar invivomriwithconcurrentexcitationandacquisitionusingautomatedactiveanalogcancellation AT jangkorvink invivomriwithconcurrentexcitationandacquisitionusingautomatedactiveanalogcancellation AT michaelbock invivomriwithconcurrentexcitationandacquisitionusingautomatedactiveanalogcancellation |