Low Lymphocyte Count Is Associated With Radiotherapy Parameters and Affects the Outcomes of Esophageal Squamous Cell Carcinoma Patients

Low Lymphocyte Count Is Associated With Radiotherapy Parameters and Affects the Outcomes of Esophageal Squamous Cell Carcinoma Patients

Purpose: Lymphocytes are central players in systemic anti-tumor immune responses. In this study, we aimed to identify the relationship between absolute lymphocyte count (ALC) nadir during definitive radiotherapy (RT) and survival outcomes in patients with esophageal squamous cell carcinoma (ESCC), a...

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Bibliographic Details
Main Authors: Xin Wang, Zongxing Zhao, Peiliang Wang, Xiaotao Geng, Liqiong Zhu, Minghuan Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Oncology
Subjects:
radiotherapy
esophageal squamous cell carcinoma
radiation-induced lymphopenia
prognosis
immunosuppression
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00997/full

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