Bioactive Polymeric Materials for the Advancement of Regenerative Medicine

Biopolymers are widely accepted natural materials in regenerative medicine, and further development of their bioactivities and discoveries on their composition/function relationships could greatly advance the field. However, a concise insight on commonly investigated biopolymers, their current appli...

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Main Authors: Anthony Iovene, Yuwen Zhao, Shue Wang, Kagya Amoako
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Journal of Functional Biomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4983/12/1/14
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author Anthony Iovene
Yuwen Zhao
Shue Wang
Kagya Amoako
author_facet Anthony Iovene
Yuwen Zhao
Shue Wang
Kagya Amoako
author_sort Anthony Iovene
collection DOAJ
description Biopolymers are widely accepted natural materials in regenerative medicine, and further development of their bioactivities and discoveries on their composition/function relationships could greatly advance the field. However, a concise insight on commonly investigated biopolymers, their current applications and outlook of their modifications for multibioactivity are scarce. This review bridges this gap for professionals and especially freshmen in the field who are also interested in modification methods not yet in commercial use. A series of polymeric materials in research and development uses are presented as well as challenges that limit their efficacy in tissue regeneration are discussed. Finally, their roles in the regeneration of select tissues including the skin, bone, cartilage, and tendon are highlighted along with modifiable biopolymer moieties for different bioactivities.
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spelling doaj.art-9240378357f14df488f1f1a06132d0502023-12-11T17:44:48ZengMDPI AGJournal of Functional Biomaterials2079-49832021-02-011211410.3390/jfb12010014Bioactive Polymeric Materials for the Advancement of Regenerative MedicineAnthony Iovene0Yuwen Zhao1Shue Wang2Kagya Amoako3Biomedical Engineering Graduate Program, Biomedical Engineering Faculty, Tagliatela College of Engineering, University of New Haven, 300 Boston Post Rd., West Haven, CT 06516, USABiomedical Engineering Graduate Program, Biomedical Engineering Faculty, Tagliatela College of Engineering, University of New Haven, 300 Boston Post Rd., West Haven, CT 06516, USABiomedical Engineering Graduate Program, Biomedical Engineering Faculty, Tagliatela College of Engineering, University of New Haven, 300 Boston Post Rd., West Haven, CT 06516, USABiomedical Engineering Graduate Program, Biomedical Engineering Faculty, Tagliatela College of Engineering, University of New Haven, 300 Boston Post Rd., West Haven, CT 06516, USABiopolymers are widely accepted natural materials in regenerative medicine, and further development of their bioactivities and discoveries on their composition/function relationships could greatly advance the field. However, a concise insight on commonly investigated biopolymers, their current applications and outlook of their modifications for multibioactivity are scarce. This review bridges this gap for professionals and especially freshmen in the field who are also interested in modification methods not yet in commercial use. A series of polymeric materials in research and development uses are presented as well as challenges that limit their efficacy in tissue regeneration are discussed. Finally, their roles in the regeneration of select tissues including the skin, bone, cartilage, and tendon are highlighted along with modifiable biopolymer moieties for different bioactivities.https://www.mdpi.com/2079-4983/12/1/14biopolymerspolymer modificationbioactivityregenerative medicinetissue regeneration
spellingShingle Anthony Iovene
Yuwen Zhao
Shue Wang
Kagya Amoako
Bioactive Polymeric Materials for the Advancement of Regenerative Medicine
Journal of Functional Biomaterials
biopolymers
polymer modification
bioactivity
regenerative medicine
tissue regeneration
title Bioactive Polymeric Materials for the Advancement of Regenerative Medicine
title_full Bioactive Polymeric Materials for the Advancement of Regenerative Medicine
title_fullStr Bioactive Polymeric Materials for the Advancement of Regenerative Medicine
title_full_unstemmed Bioactive Polymeric Materials for the Advancement of Regenerative Medicine
title_short Bioactive Polymeric Materials for the Advancement of Regenerative Medicine
title_sort bioactive polymeric materials for the advancement of regenerative medicine
topic biopolymers
polymer modification
bioactivity
regenerative medicine
tissue regeneration
url https://www.mdpi.com/2079-4983/12/1/14
work_keys_str_mv AT anthonyiovene bioactivepolymericmaterialsfortheadvancementofregenerativemedicine
AT yuwenzhao bioactivepolymericmaterialsfortheadvancementofregenerativemedicine
AT shuewang bioactivepolymericmaterialsfortheadvancementofregenerativemedicine
AT kagyaamoako bioactivepolymericmaterialsfortheadvancementofregenerativemedicine