Anticholinergic Drugs in Nonallergic Rhinitis
Background: The parasympathetic nervous system contributes to the pathophysiology of multiple forms of allergic and nonallergic rhinitis. Stimulation of the parasympathetic nervous system leads to glandular activation, which produces watery secretions. In excess, these secretions discharge from the...
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| Format: | Article |
| Language: | English |
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Elsevier
2009-01-01
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| Series: | World Allergy Organization Journal |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1939455119305447 |
| _version_ | 1818511628897878016 |
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| author | Robert Naclerio, MD |
| author_facet | Robert Naclerio, MD |
| author_sort | Robert Naclerio, MD |
| collection | DOAJ |
| description | Background: The parasympathetic nervous system contributes to the pathophysiology of multiple forms of allergic and nonallergic rhinitis. Stimulation of the parasympathetic nervous system leads to glandular activation, which produces watery secretions. In excess, these secretions discharge from the anterior Nares and produce the symptom of watery anterior rhinorrhea.Method: Review of literature.Results: Treatment with topical, intranasal anticholinergic drugs inhibits activation of the nasal mucosal glands and is effective in reducing the watery secretions associated with parasympathetic stimulation of the glands with little, if any, effect on the symptoms of congestion and sneezing. In general, these drugs have no systemic adverse effects, but can cause crusting and local irritation.Conclusion: Anticholinergic drugs are useful for the treatment of anterior rhinorrhea associated with allergic and nonallergic rhinitis. Keywords: anticholinergic, atropine, ipratropium bromide, rhinitis, nonallergic rhinitis |
| first_indexed | 2024-12-10T23:35:40Z |
| format | Article |
| id | doaj.art-9241e3b46e8a4a7db10b6b4dcccc85d2 |
| institution | Directory Open Access Journal |
| issn | 1939-4551 |
| language | English |
| last_indexed | 2024-12-10T23:35:40Z |
| publishDate | 2009-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | World Allergy Organization Journal |
| spelling | doaj.art-9241e3b46e8a4a7db10b6b4dcccc85d22022-12-22T01:29:12ZengElsevierWorld Allergy Organization Journal1939-45512009-01-0128162165Anticholinergic Drugs in Nonallergic RhinitisRobert Naclerio, MD0Corresponding author.; Section of Otolaryngology—Head and Neck Surgery, The University of Chicago, Chicago, ILBackground: The parasympathetic nervous system contributes to the pathophysiology of multiple forms of allergic and nonallergic rhinitis. Stimulation of the parasympathetic nervous system leads to glandular activation, which produces watery secretions. In excess, these secretions discharge from the anterior Nares and produce the symptom of watery anterior rhinorrhea.Method: Review of literature.Results: Treatment with topical, intranasal anticholinergic drugs inhibits activation of the nasal mucosal glands and is effective in reducing the watery secretions associated with parasympathetic stimulation of the glands with little, if any, effect on the symptoms of congestion and sneezing. In general, these drugs have no systemic adverse effects, but can cause crusting and local irritation.Conclusion: Anticholinergic drugs are useful for the treatment of anterior rhinorrhea associated with allergic and nonallergic rhinitis. Keywords: anticholinergic, atropine, ipratropium bromide, rhinitis, nonallergic rhinitishttp://www.sciencedirect.com/science/article/pii/S1939455119305447 |
| spellingShingle | Robert Naclerio, MD Anticholinergic Drugs in Nonallergic Rhinitis World Allergy Organization Journal |
| title | Anticholinergic Drugs in Nonallergic Rhinitis |
| title_full | Anticholinergic Drugs in Nonallergic Rhinitis |
| title_fullStr | Anticholinergic Drugs in Nonallergic Rhinitis |
| title_full_unstemmed | Anticholinergic Drugs in Nonallergic Rhinitis |
| title_short | Anticholinergic Drugs in Nonallergic Rhinitis |
| title_sort | anticholinergic drugs in nonallergic rhinitis |
| url | http://www.sciencedirect.com/science/article/pii/S1939455119305447 |
| work_keys_str_mv | AT robertnacleriomd anticholinergicdrugsinnonallergicrhinitis |