Estrogens Promote the Production of Natural Neutralizing Antibodies in Fish through G Protein-Coupled Estrogen Receptor 1

Estrogens Promote the Production of Natural Neutralizing Antibodies in Fish through G Protein-Coupled Estrogen Receptor 1

Natural antibodies play crucial roles in pathogen elimination, B-cell survival and homeostasis, and inflammatory and autoimmune diseases. Although estrogens are able to regulate both innate and adaptive immune responses, their role in the production of natural antibodies is unknown. Here, we show th...

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Bibliographic Details
Main Authors: María C. Rodenas, Isabel Cabas, Nuria E. Gómez-González, Marta Arizcun, José Meseguer, Victoriano Mulero, Alfonsa García-Ayala
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Immunology
Subjects:
G protein-coupled estrogen receptor 1
estrogens
lymphocytes
natural antibodies
evolution
fish
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00736/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00736/full

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