Comparison of outcomes and side effects for neoadjuvant chemotherapy with weekly cisplatin and paclitaxel followed by chemoradiation vs. chemoradiation alone in stage IIB–IVA cervical cancer: study protocol for a randomized controlled trial

Comparison of outcomes and side effects for neoadjuvant chemotherapy with weekly cisplatin and paclitaxel followed by chemoradiation vs. chemoradiation alone in stage IIB–IVA cervical cancer: study protocol for a randomized controlled trial

Abstract Background Currently, the standard treatment for locally advanced cervical cancer is concurrent chemoradiation (CCRT). The effect of neoadjuvant chemotherapy in advanced cervical cancer is controversial. Studies have shown that the addition of a weekly regimen of neoadjuvant chemotherapy (N...

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Bibliographic Details
Main Authors: Jing Li, Hua Liu, Ya Li, Jian Li, Lifei Shen, Wenqing Long, Chenmin Yang, Haoping Xu, Wenqi Xi, Rong Cai, Weiwei Feng
Format: Article
Language:English
Published: BMC 2022-01-01
Series:Trials
Subjects:
Dose-dense neoadjuvant chemotherapy
Weekly cisplatin/paclitaxel
Concurrent chemoradiotherapy (CCRT)
Stage IIB–IVA cervical cancer
Online Access:https://doi.org/10.1186/s13063-021-05986-z

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