CD36<sup>+</sup> Fibroblasts Secrete Protein Ligands That Growth-Suppress Triple-Negative Breast Cancer Cells While Elevating Adipogenic Markers for a Model of Cancer-Associated Fibroblast

CD36<sup>+</sup> Fibroblasts Secrete Protein Ligands That Growth-Suppress Triple-Negative Breast Cancer Cells While Elevating Adipogenic Markers for a Model of Cancer-Associated Fibroblast

Tumor and stroma coevolve to facilitate tumor growth. Hence, effective tumor therapeutics would not only induce growth suppression of tumor cells but also revert pro-tumor stroma into anti-tumoral type. Previously, we showed that coculturing triple-negative or luminal A breast cancer cells with CD36...

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Bibliographic Details
Main Authors: Kosar Jabbari, Qingsu Cheng, Garrett Winkelmaier, Saori Furuta, Bahram Parvin
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:International Journal of Molecular Sciences
Subjects:
CD36<sup>+</sup> fibroblasts
tumor suppression
cancer-associated fibroblasts
stromal reprogramming
Online Access:https://www.mdpi.com/1422-0067/23/21/12744

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