Analysis of the key ligand receptor CADM1_CADM1 in the regulation of thyroid cancer based on scRNA-seq and bulk RNA-seq data

Analysis of the key ligand receptor CADM1_CADM1 in the regulation of thyroid cancer based on scRNA-seq and bulk RNA-seq data

IntroductionAdvanced papillary thyroid cancer (PTC) has a poor prognosis, 60~70% of which become radio iodine refractory (RAI-R), but the molecular markers that assess PTC progress to advanced PTC remain unclear. Meanwhile, current targeted therapies are badly effective due to drug resistance and ad...

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Bibliographic Details
Main Authors: Hui He, Shan Cong, Yu Wang, Qinghai Ji, Weiyan Liu, Ning Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Endocrinology
Subjects:
advanced PTC
ligand-receptor pair
CADM1_CADM1
targeted therapy
prognostic biomarker
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.969914/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.969914/full

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