Novel Associations Between METTL3 Gene Polymorphisms and Pediatric Acute Lymphoblastic Leukemia: A Five-Center Case-Control Study

Novel Associations Between METTL3 Gene Polymorphisms and Pediatric Acute Lymphoblastic Leukemia: A Five-Center Case-Control Study

ObjectiveTo reveal the contributing role of METTL3 gene SNPs in pediatric ALL risk.Patients and MethodsA total of 808 pediatric ALL cases and 1,340 cancer-free controls from five hospitals in South China were recruited. A case-control study by genotyping three SNPs in the METTL3 gene was conducted....

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Bibliographic Details
Main Authors: Xiaoping Liu, Libin Huang, Ke Huang, Lihua Yang, Xu Yang, Ailing Luo, Mansi Cai, Xuedong Wu, Xiaodan Liu, Yaping Yan, Jianyun Wen, Yun Cai, Ling Xu, Hua Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Oncology
Subjects:
methyltransferase-like 3
acute lymphoid leukemia
polymorphism
pediatric
susceptibility
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.635251/full

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