Perfusion index as a predictor of hypotension after induction of general anesthesia in elderly patients – a prospective observational study

ABSTRACTIntroduction The elderly patients are at a greater risk for hypotension after induction of anesthesia. Perfusion index (PI) predicted patients vascular responses in many situations. This study hypothesized that baseline value of PI would predict hypotension in geriatric patients after anesth...

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Main Authors: Sherif Abdullah Mohamed, Mona Yousry Helmy, Sara A Khattab, Ayman Mohammed Hossam, Mohamed S. Arafa
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Egyptian Journal of Anaesthesia
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/11101849.2023.2238524
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author Sherif Abdullah Mohamed
Mona Yousry Helmy
Sara A Khattab
Ayman Mohammed Hossam
Mohamed S. Arafa
author_facet Sherif Abdullah Mohamed
Mona Yousry Helmy
Sara A Khattab
Ayman Mohammed Hossam
Mohamed S. Arafa
author_sort Sherif Abdullah Mohamed
collection DOAJ
description ABSTRACTIntroduction The elderly patients are at a greater risk for hypotension after induction of anesthesia. Perfusion index (PI) predicted patients vascular responses in many situations. This study hypothesized that baseline value of PI would predict hypotension in geriatric patients after anesthetic induction as population at risk for postinduction hypotension.Methods This observational, prospective study involved 30 patients aged >65 years who were scheduled for elective procedures under general anesthesia. From baseline to 15 min after propofol induction of anesthesia, the PI, heart rate, and blood pressure (BP) were recorded every minute. Hypotension was defined as a decrease greater than 30% in systolic BP from baseline.Results Early hypotension within 3 min after induction was experienced in 53.3%, while 36.7% had late hypotension within 15 min. Receiver operating characteristic (ROC) curves for PI as a predictive test of hypotension at 3 min showed good predictability of the baseline PI for early postinduction hypotension with area under receiver operating characteristic curve (AUC) 0.97, sensitivity 88%, specificity 93%, positive predictive value (PPV) 93%, negative predictive value (NPV) 87%, and a cutoff value of ≤1.3. After intubation, the predictive value decreased, with PI > 0.91 to predict late hypotension with sensitivity 91%, specificity 58%, PPV 56%, NPV 92%, and AUC 0.66.Conclusions PI could predict early hypotension following propofol induction in the geriatric population. So, it can be considered a valuable tool in monitoring this vulnerable population after induction of anesthesia.
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spelling doaj.art-924b7e3102584282b4ecf1408223400c2023-07-25T12:41:27ZengTaylor & Francis GroupEgyptian Journal of Anaesthesia1110-18492023-12-0139161962510.1080/11101849.2023.2238524Perfusion index as a predictor of hypotension after induction of general anesthesia in elderly patients – a prospective observational studySherif Abdullah Mohamed0Mona Yousry Helmy1Sara A Khattab2Ayman Mohammed Hossam3Mohamed S. Arafa4Anesthesia, Faculty of Medicine, Cairo University, Cairo, EgyptLecturer of Internal Medicine, Cairo University, Cairo, EgyptAnesthesia, Surgical ICU and Pain Management, Cairo University, Cairo, EgyptAnesthesia, Surgical ICU and Pain Management, Cairo University, Cairo, EgyptLecturer of Internal Medicine, Cairo University, Cairo, EgyptABSTRACTIntroduction The elderly patients are at a greater risk for hypotension after induction of anesthesia. Perfusion index (PI) predicted patients vascular responses in many situations. This study hypothesized that baseline value of PI would predict hypotension in geriatric patients after anesthetic induction as population at risk for postinduction hypotension.Methods This observational, prospective study involved 30 patients aged >65 years who were scheduled for elective procedures under general anesthesia. From baseline to 15 min after propofol induction of anesthesia, the PI, heart rate, and blood pressure (BP) were recorded every minute. Hypotension was defined as a decrease greater than 30% in systolic BP from baseline.Results Early hypotension within 3 min after induction was experienced in 53.3%, while 36.7% had late hypotension within 15 min. Receiver operating characteristic (ROC) curves for PI as a predictive test of hypotension at 3 min showed good predictability of the baseline PI for early postinduction hypotension with area under receiver operating characteristic curve (AUC) 0.97, sensitivity 88%, specificity 93%, positive predictive value (PPV) 93%, negative predictive value (NPV) 87%, and a cutoff value of ≤1.3. After intubation, the predictive value decreased, with PI > 0.91 to predict late hypotension with sensitivity 91%, specificity 58%, PPV 56%, NPV 92%, and AUC 0.66.Conclusions PI could predict early hypotension following propofol induction in the geriatric population. So, it can be considered a valuable tool in monitoring this vulnerable population after induction of anesthesia.https://www.tandfonline.com/doi/10.1080/11101849.2023.2238524Perfusion indexPostinduction hypotensionGeriatric patientsGeneral anesthesia
spellingShingle Sherif Abdullah Mohamed
Mona Yousry Helmy
Sara A Khattab
Ayman Mohammed Hossam
Mohamed S. Arafa
Perfusion index as a predictor of hypotension after induction of general anesthesia in elderly patients – a prospective observational study
Egyptian Journal of Anaesthesia
Perfusion index
Postinduction hypotension
Geriatric patients
General anesthesia
title Perfusion index as a predictor of hypotension after induction of general anesthesia in elderly patients – a prospective observational study
title_full Perfusion index as a predictor of hypotension after induction of general anesthesia in elderly patients – a prospective observational study
title_fullStr Perfusion index as a predictor of hypotension after induction of general anesthesia in elderly patients – a prospective observational study
title_full_unstemmed Perfusion index as a predictor of hypotension after induction of general anesthesia in elderly patients – a prospective observational study
title_short Perfusion index as a predictor of hypotension after induction of general anesthesia in elderly patients – a prospective observational study
title_sort perfusion index as a predictor of hypotension after induction of general anesthesia in elderly patients a prospective observational study
topic Perfusion index
Postinduction hypotension
Geriatric patients
General anesthesia
url https://www.tandfonline.com/doi/10.1080/11101849.2023.2238524
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