Plant-Derived Sulforaphane Suppresses Growth and Proliferation of Drug-Sensitive and Drug-Resistant Bladder Cancer Cell Lines In Vitro

Plant-Derived Sulforaphane Suppresses Growth and Proliferation of Drug-Sensitive and Drug-Resistant Bladder Cancer Cell Lines In Vitro

Combined cisplatin–gemcitabine (GC) application is standard for treating muscle-invasive bladder cancer. However, since rapid resistance to treatment often develops, many patients turn to supplements in the form of plant-based compounds. Sulforaphane (SFN), derived from cruciferous vegetables, is on...

Full description

Bibliographic Details
Main Authors: Hui Xie, Jochen Rutz, Sebastian Maxeiner, Timothy Grein, Anita Thomas, Eva Juengel, Felix K.-H. Chun, Jindrich Cinatl, Axel Haferkamp, Igor Tsaur, Roman A. Blaheta
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cancers
Subjects:
sulforaphane
bladder cancer
drug resistance
proliferation
AKT/mTOR
Online Access:https://www.mdpi.com/2072-6694/14/19/4682

Internet

https://www.mdpi.com/2072-6694/14/19/4682

Similar Items