Cinnamic Acid Derivatives as Cardioprotective Agents against Oxidative and Structural Damage Induced by Doxorubicin

Cinnamic Acid Derivatives as Cardioprotective Agents against Oxidative and Structural Damage Induced by Doxorubicin

Doxorubicin (DOX) is a widely used anticancer drug. However, its clinical use is severely limited due to drug-induced cumulative cardiotoxicity, which leads to progressive cardiomyocyte dysfunction and heart failure. Enormous efforts have been made to identify potential strategies to alleviate DOX-i...

Full description

Bibliographic Details
Main Authors: Paulina Koczurkiewicz-Adamczyk, Katarzyna Klaś, Agnieszka Gunia-Krzyżak, Kamil Piska, Kalina Andrysiak, Jacek Stępniewski, Sławomir Lasota, Katarzyna Wójcik-Pszczoła, Józef Dulak, Zbigniew Madeja, Elżbieta Pękala
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
doxorubicin
cardiotoxicity
combined therapy
cinnamic acid derivatives
cardioprotection
hiPSC-CM
Online Access:https://www.mdpi.com/1422-0067/22/12/6217

Internet

https://www.mdpi.com/1422-0067/22/12/6217

Similar Items