Supportive Care in Pediatric Oncology: Opportunities and Future Directions
The optimization of outcomes for pediatric cancer patients relies on the successful advancement of supportive care to ease the treatment burden and mitigate the long-term impacts of cancer therapy. Advancing pediatric supportive care requires research prioritization as well as the development and im...
| Main Authors: | , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-11-01
|
| Series: | Cancers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2072-6694/15/23/5549 |
| _version_ | 1797400393144074240 |
|---|---|
| author | Jason L. Freedman Dori M. Beeler Alison Bowers Natalie Bradford Yin Ting Cheung Maya Davies L. Lee Dupuis Caitlin W. Elgarten Torri M. Jones Tracey Jubelirer Tamara P. Miller Priya Patel Charles A. Phillips Hannah R. Wardill Andrea D. Orsey |
| author_facet | Jason L. Freedman Dori M. Beeler Alison Bowers Natalie Bradford Yin Ting Cheung Maya Davies L. Lee Dupuis Caitlin W. Elgarten Torri M. Jones Tracey Jubelirer Tamara P. Miller Priya Patel Charles A. Phillips Hannah R. Wardill Andrea D. Orsey |
| author_sort | Jason L. Freedman |
| collection | DOAJ |
| description | The optimization of outcomes for pediatric cancer patients relies on the successful advancement of supportive care to ease the treatment burden and mitigate the long-term impacts of cancer therapy. Advancing pediatric supportive care requires research prioritization as well as the development and implementation of innovations. Like the prevailing theme throughout pediatric oncology, there is a clear need for personalized or precision approaches that are consistent, evidence-based, and guided by clinical practice guidelines. By incorporating technology and datasets, we can address questions which may not be feasible to explore in clinical trials. Now is the time to listen to patients’ voices by using patient-reported outcomes (PROs) to ensure that their contributions and experiences inform clinical care plans. Furthermore, while the extrapolation of knowledge and approaches from adult populations may suffice in the absence of pediatric-specific evidence, there is a critical need to specifically understand and implement elements of general and developmental pediatrics like growth, nutrition, development, and physical activity into care. Increased research funding for pediatric supportive care is critical to address resource availability, equity, and disparities across the globe. Our patients deserve to enjoy healthy, productive lives with optimized and enriched supportive care that spans the spectrum from diagnosis to survivorship. |
| first_indexed | 2024-03-09T01:54:22Z |
| format | Article |
| id | doaj.art-925865d61d344fb2a887de68aabdc278 |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-09T01:54:22Z |
| publishDate | 2023-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-925865d61d344fb2a887de68aabdc2782023-12-08T15:12:30ZengMDPI AGCancers2072-66942023-11-011523554910.3390/cancers15235549Supportive Care in Pediatric Oncology: Opportunities and Future DirectionsJason L. Freedman0Dori M. Beeler1Alison Bowers2Natalie Bradford3Yin Ting Cheung4Maya Davies5L. Lee Dupuis6Caitlin W. Elgarten7Torri M. Jones8Tracey Jubelirer9Tamara P. Miller10Priya Patel11Charles A. Phillips12Hannah R. Wardill13Andrea D. Orsey14Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USADepartment of Supportive Oncology, Levine Cancer Institute, Atrium Health, Charlotte, NC 28204, USACancer and Palliative Care Outcomes Centre, Centre for Children’s Health Research, Queensland University of Technology, Brisbane City, QLD 4000, AustraliaCancer and Palliative Care Outcomes Centre, Centre for Children’s Health Research, Queensland University of Technology, Brisbane City, QLD 4000, AustraliaSchool of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, ChinaSchool of Biomedicine, The Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA 5005, AustraliaLeslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 1A1, CanadaDepartment of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USADivision of Oncology, Children’s Hospital of Philadelphia, Philadelphia, PA 19104, USADepartment of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USAAflac Cancer & Blood Disorders Center, Children’s Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA 30322, USADepartment of Pharmacy, The Hospital for Sick Children, Toronto, ON M5G 1E8, CanadaDepartment of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USASchool of Biomedicine, The Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, SA 5005, AustraliaCenter for Cancer and Blood Disorders, Connecticut Children’s Medical Center, Hartford, CT 06106, USAThe optimization of outcomes for pediatric cancer patients relies on the successful advancement of supportive care to ease the treatment burden and mitigate the long-term impacts of cancer therapy. Advancing pediatric supportive care requires research prioritization as well as the development and implementation of innovations. Like the prevailing theme throughout pediatric oncology, there is a clear need for personalized or precision approaches that are consistent, evidence-based, and guided by clinical practice guidelines. By incorporating technology and datasets, we can address questions which may not be feasible to explore in clinical trials. Now is the time to listen to patients’ voices by using patient-reported outcomes (PROs) to ensure that their contributions and experiences inform clinical care plans. Furthermore, while the extrapolation of knowledge and approaches from adult populations may suffice in the absence of pediatric-specific evidence, there is a critical need to specifically understand and implement elements of general and developmental pediatrics like growth, nutrition, development, and physical activity into care. Increased research funding for pediatric supportive care is critical to address resource availability, equity, and disparities across the globe. Our patients deserve to enjoy healthy, productive lives with optimized and enriched supportive care that spans the spectrum from diagnosis to survivorship.https://www.mdpi.com/2072-6694/15/23/5549pediatricssupportive careclinical practice guidelinesCPGPROpalliative care |
| spellingShingle | Jason L. Freedman Dori M. Beeler Alison Bowers Natalie Bradford Yin Ting Cheung Maya Davies L. Lee Dupuis Caitlin W. Elgarten Torri M. Jones Tracey Jubelirer Tamara P. Miller Priya Patel Charles A. Phillips Hannah R. Wardill Andrea D. Orsey Supportive Care in Pediatric Oncology: Opportunities and Future Directions Cancers pediatrics supportive care clinical practice guidelines CPG PRO palliative care |
| title | Supportive Care in Pediatric Oncology: Opportunities and Future Directions |
| title_full | Supportive Care in Pediatric Oncology: Opportunities and Future Directions |
| title_fullStr | Supportive Care in Pediatric Oncology: Opportunities and Future Directions |
| title_full_unstemmed | Supportive Care in Pediatric Oncology: Opportunities and Future Directions |
| title_short | Supportive Care in Pediatric Oncology: Opportunities and Future Directions |
| title_sort | supportive care in pediatric oncology opportunities and future directions |
| topic | pediatrics supportive care clinical practice guidelines CPG PRO palliative care |
| url | https://www.mdpi.com/2072-6694/15/23/5549 |
| work_keys_str_mv | AT jasonlfreedman supportivecareinpediatriconcologyopportunitiesandfuturedirections AT dorimbeeler supportivecareinpediatriconcologyopportunitiesandfuturedirections AT alisonbowers supportivecareinpediatriconcologyopportunitiesandfuturedirections AT nataliebradford supportivecareinpediatriconcologyopportunitiesandfuturedirections AT yintingcheung supportivecareinpediatriconcologyopportunitiesandfuturedirections AT mayadavies supportivecareinpediatriconcologyopportunitiesandfuturedirections AT lleedupuis supportivecareinpediatriconcologyopportunitiesandfuturedirections AT caitlinwelgarten supportivecareinpediatriconcologyopportunitiesandfuturedirections AT torrimjones supportivecareinpediatriconcologyopportunitiesandfuturedirections AT traceyjubelirer supportivecareinpediatriconcologyopportunitiesandfuturedirections AT tamarapmiller supportivecareinpediatriconcologyopportunitiesandfuturedirections AT priyapatel supportivecareinpediatriconcologyopportunitiesandfuturedirections AT charlesaphillips supportivecareinpediatriconcologyopportunitiesandfuturedirections AT hannahrwardill supportivecareinpediatriconcologyopportunitiesandfuturedirections AT andreadorsey supportivecareinpediatriconcologyopportunitiesandfuturedirections |