Laminin-bound integrin α6β4 promotes non-small cell lung cancer progression via the activation of YAP/TAZ signaling pathway

Laminin-bound integrin α6β4 promotes non-small cell lung cancer progression via the activation of YAP/TAZ signaling pathway

Laminin is an extracellular matrix multidomain trimeric glycoprotein, that has a potential role in tumor progression. Here, we studied the effects of non-small cell lung cancer (NSCLC) cells interaction on laminin and explored the underlying mechanism of laminin associated NSCLC progression. Culture...

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Bibliographic Details
Main Authors: Xiaopeng Zhao, Chuang Liu, Xu He, Miao Wang, Haoran Zhang, Jingge Cheng, Hongyan Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Oncology
Subjects:
laminin
integrin α6β4
nsclc
YAP/TAZ signaling
tumor progression
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1015709/full

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