Chronic Uridine Administration Induces Fatty Liver and Pre-Diabetic Conditions in Mice.
Uridine is a pyrimidine nucleoside that exerts restorative functions in tissues under stress. Short-term co-administration of uridine with multiple unrelated drugs prevents drug-induced liver lipid accumulation. Uridine has the ability to modulate liver metabolism; however, the precise mechanism has...
Main Authors: | Yasuyo Urasaki, Giuseppe Pizzorno, Thuc T Le |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4720477?pdf=render |
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