Optimizing early neurological deterioration prediction in acute ischemic stroke patients following intravenous thrombolysis: a LASSO regression model approach

Optimizing early neurological deterioration prediction in acute ischemic stroke patients following intravenous thrombolysis: a LASSO regression model approach

BackgroundAcute ischemic stroke (AIS) remains a leading cause of disability and mortality globally among adults. Despite Intravenous Thrombolysis (IVT) with recombinant tissue plasminogen activator (rt-PA) emerging as the standard treatment for AIS, approximately 6–40% of patients undergoing IVT exp...

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Bibliographic Details
Main Authors: Ning Li, Ying-Lei Li, Jia-Min Shao, Chu-Han Wang, Si-Bo Li, Ye Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Neuroscience
Subjects:
acute ischemic stroke (AIS)
intravenous thrombolysis (IVT)
early neurological deterioration (END)
LASSO regression
predictive modeling
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2024.1390117/full

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