Mechanistic Insight Into the Interaction Between Helicobacter pylori Urease Subunit α and Its Molecular Chaperone Hsp60

Mechanistic Insight Into the Interaction Between Helicobacter pylori Urease Subunit α and Its Molecular Chaperone Hsp60

Helicobacter pylori is the etiologic agent in a variety of gastroduodenal diseases. As its key pathogenic factors, both urease and Hsp60 play important roles in the pathogenesis of H. pylori. Previous studies have suggested that there is close relationship between urease and Hsp60, which implied tha...

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Bibliographic Details
Main Authors: Huilin Zhao, Yulong Wu, Zheng Xu, Ran Ma, Yunfei Ding, Xuelian Bai, Qianyu Rong, Ying Zhang, Boqing Li, Xiaofei Ji
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Microbiology
Subjects:
Helicobacter pylori
urease
Hsp60
chaperone
protein–protein interaction
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00153/full

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