Distributions and Trends of the Global Burden of Colorectal Cancer Attributable to Dietary Risk Factors over the Past 30 Years
Dietary risk has always been a major risk factor for colorectal cancer (CRC). However, the contribution of dietary risk factors to CRC at the level of region, gender, and age has not been fully characterized. Based on the Global Burden of Disease (GBD) 2019 study, the death rates, age-standardized m...
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MDPI AG
2023-12-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/16/1/132 |
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| author | Yuxing Liang Nan Zhang Miao Wang Yixin Liu Linlu Ma Qian Wang Qian Yang Xiaoyan Liu Fuling Zhou Yongchang Wei |
| author_facet | Yuxing Liang Nan Zhang Miao Wang Yixin Liu Linlu Ma Qian Wang Qian Yang Xiaoyan Liu Fuling Zhou Yongchang Wei |
| author_sort | Yuxing Liang |
| collection | DOAJ |
| description | Dietary risk has always been a major risk factor for colorectal cancer (CRC). However, the contribution of dietary risk factors to CRC at the level of region, gender, and age has not been fully characterized. Based on the Global Burden of Disease (GBD) 2019 study, the death rates, age-standardized mortality rates (ASDRs), and estimated annual percentage changes (EAPCs) were calculated to assess the trends of CRC attributable to dietary risk factors over the past 30 years. Globally, the death cases of CRC increased to 1,085,797 in 2019, and the number of deaths attributed to dietary risk factors increased to 365,752 in 2019, representing approximately one-third of all CRC-related fatalities. Overall, the ASDR attributable to dietary risks was 4.61 per 100,000 in 2019, with a slight downward trend (EAPC = −0.29). Notably, there is a rising trend in early-onset colorectal cancer mortality associated with dietary factors. To alleviate CRC burdens, it is recommended to elevate the intake of whole grains, milk, calcium, and fiber while reducing consumption of red and processed meats. The results will improve the understanding, and provide guidance on the diet of CRC in different regions, gender, and age groups worldwide. |
| first_indexed | 2024-03-08T15:00:32Z |
| format | Article |
| id | doaj.art-9265cc74cc3a42f8877d841c90f44077 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-08T15:00:32Z |
| publishDate | 2023-12-01 |
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| spelling | doaj.art-9265cc74cc3a42f8877d841c90f440772024-01-10T15:05:40ZengMDPI AGNutrients2072-66432023-12-0116113210.3390/nu16010132Distributions and Trends of the Global Burden of Colorectal Cancer Attributable to Dietary Risk Factors over the Past 30 YearsYuxing Liang0Nan Zhang1Miao Wang2Yixin Liu3Linlu Ma4Qian Wang5Qian Yang6Xiaoyan Liu7Fuling Zhou8Yongchang Wei9Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaDepartment of Hematology, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaDepartment of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaDepartment of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaDepartment of Hematology, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaDepartment of Hematology, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaDepartment of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaDepartment of Hematology, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaDepartment of Hematology, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaDepartment of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan 430071, ChinaDietary risk has always been a major risk factor for colorectal cancer (CRC). However, the contribution of dietary risk factors to CRC at the level of region, gender, and age has not been fully characterized. Based on the Global Burden of Disease (GBD) 2019 study, the death rates, age-standardized mortality rates (ASDRs), and estimated annual percentage changes (EAPCs) were calculated to assess the trends of CRC attributable to dietary risk factors over the past 30 years. Globally, the death cases of CRC increased to 1,085,797 in 2019, and the number of deaths attributed to dietary risk factors increased to 365,752 in 2019, representing approximately one-third of all CRC-related fatalities. Overall, the ASDR attributable to dietary risks was 4.61 per 100,000 in 2019, with a slight downward trend (EAPC = −0.29). Notably, there is a rising trend in early-onset colorectal cancer mortality associated with dietary factors. To alleviate CRC burdens, it is recommended to elevate the intake of whole grains, milk, calcium, and fiber while reducing consumption of red and processed meats. The results will improve the understanding, and provide guidance on the diet of CRC in different regions, gender, and age groups worldwide.https://www.mdpi.com/2072-6643/16/1/132global burden of diseasedietary risk factorscolorectal cancerprevention |
| spellingShingle | Yuxing Liang Nan Zhang Miao Wang Yixin Liu Linlu Ma Qian Wang Qian Yang Xiaoyan Liu Fuling Zhou Yongchang Wei Distributions and Trends of the Global Burden of Colorectal Cancer Attributable to Dietary Risk Factors over the Past 30 Years Nutrients global burden of disease dietary risk factors colorectal cancer prevention |
| title | Distributions and Trends of the Global Burden of Colorectal Cancer Attributable to Dietary Risk Factors over the Past 30 Years |
| title_full | Distributions and Trends of the Global Burden of Colorectal Cancer Attributable to Dietary Risk Factors over the Past 30 Years |
| title_fullStr | Distributions and Trends of the Global Burden of Colorectal Cancer Attributable to Dietary Risk Factors over the Past 30 Years |
| title_full_unstemmed | Distributions and Trends of the Global Burden of Colorectal Cancer Attributable to Dietary Risk Factors over the Past 30 Years |
| title_short | Distributions and Trends of the Global Burden of Colorectal Cancer Attributable to Dietary Risk Factors over the Past 30 Years |
| title_sort | distributions and trends of the global burden of colorectal cancer attributable to dietary risk factors over the past 30 years |
| topic | global burden of disease dietary risk factors colorectal cancer prevention |
| url | https://www.mdpi.com/2072-6643/16/1/132 |
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