Accelerated growth plate mineralization and foreshortened proximal limb bones in fetuin-A knockout mice.

Accelerated growth plate mineralization and foreshortened proximal limb bones in fetuin-A knockout mice.

The plasma protein fetuin-A/alpha2-HS-glycoprotein (genetic symbol Ahsg) is a systemic inhibitor of extraskeletal mineralization, which is best underscored by the excessive mineral deposition found in various tissues of fetuin-A deficient mice on the calcification-prone genetic background DBA/2. Fet...

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Bibliographic Details
Main Authors: Jong Seto, Björn Busse, Himadri S Gupta, Cora Schäfer, Stefanie Krauss, John W C Dunlop, Admir Masic, Michael Kerschnitzki, Paul Zaslansky, Peter Boesecke, Philip Catalá-Lehnen, Thorsten Schinke, Peter Fratzl, Willi Jahnen-Dechent
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3473050?pdf=render

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