Severe asthma patient with secondary Citrobacter koseri abdominal infection: first case report and review of the literature
Abstract Citrobacter koseri (C. koseri) is a Gram-negative, motile, non-spore-forming facultative anaerobic bacillus belonging to the Enterobacteriaceae family. C. koseri typically utilizes citrate as the sole carbon source and constitutes part of the normal gastrointestinal flora in humans and anim...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-10-01
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| Series: | Gut Pathogens |
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| Online Access: | https://doi.org/10.1186/s13099-023-00574-9 |
| _version_ | 1797559413049917440 |
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| author | Mo Xian Xiaolong Ji Mingyu Zhong Danhong Su Jing Guan Ruchong Chen |
| author_facet | Mo Xian Xiaolong Ji Mingyu Zhong Danhong Su Jing Guan Ruchong Chen |
| author_sort | Mo Xian |
| collection | DOAJ |
| description | Abstract Citrobacter koseri (C. koseri) is a Gram-negative, motile, non-spore-forming facultative anaerobic bacillus belonging to the Enterobacteriaceae family. C. koseri typically utilizes citrate as the sole carbon source and constitutes part of the normal gastrointestinal flora in humans and animals. As an opportunistic pathogen, C. koseri infections are mainly observed in neonates, elderly individuals, and immunocompromised hosts. C. koseri has been one of the main etiological agents of neonatal meningitis and cerebral abscess. In recent years, an increasing number of cases have been reported in adults with severe infections caused by C. koseri. Here, we report for the first time a clinical case of concurrent C. koseri intra-abdominal infection in a patient with severe asthma and provide a brief review of the relevant literature. With this report, we hope to increase awareness and alertness among clinicians to the possibility of concurrent infection of gut commensal bacteria in asthmatic patients requiring long-term oral corticosteroid administration. |
| first_indexed | 2024-03-10T17:45:06Z |
| format | Article |
| id | doaj.art-9267d65a5a8946578875b1b297ac9dba |
| institution | Directory Open Access Journal |
| issn | 1757-4749 |
| language | English |
| last_indexed | 2024-03-10T17:45:06Z |
| publishDate | 2023-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Gut Pathogens |
| spelling | doaj.art-9267d65a5a8946578875b1b297ac9dba2023-11-20T09:33:08ZengBMCGut Pathogens1757-47492023-10-011511710.1186/s13099-023-00574-9Severe asthma patient with secondary Citrobacter koseri abdominal infection: first case report and review of the literatureMo Xian0Xiaolong Ji1Mingyu Zhong2Danhong Su3Jing Guan4Ruchong Chen5State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Department of Allergy and Clinical Immunology, The First Affiliated Hospital of Guangzhou Medical UniversityState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Department of Allergy and Clinical Immunology, The First Affiliated Hospital of Guangzhou Medical UniversityState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Department of Allergy and Clinical Immunology, The First Affiliated Hospital of Guangzhou Medical UniversityDepartment of Laboratory Medicine, The First Affiliated Hospital of Guangzhou Medical UniversityDepartment of Laboratory Medicine, The First Affiliated Hospital of Guangzhou Medical UniversityState Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Department of Allergy and Clinical Immunology, The First Affiliated Hospital of Guangzhou Medical UniversityAbstract Citrobacter koseri (C. koseri) is a Gram-negative, motile, non-spore-forming facultative anaerobic bacillus belonging to the Enterobacteriaceae family. C. koseri typically utilizes citrate as the sole carbon source and constitutes part of the normal gastrointestinal flora in humans and animals. As an opportunistic pathogen, C. koseri infections are mainly observed in neonates, elderly individuals, and immunocompromised hosts. C. koseri has been one of the main etiological agents of neonatal meningitis and cerebral abscess. In recent years, an increasing number of cases have been reported in adults with severe infections caused by C. koseri. Here, we report for the first time a clinical case of concurrent C. koseri intra-abdominal infection in a patient with severe asthma and provide a brief review of the relevant literature. With this report, we hope to increase awareness and alertness among clinicians to the possibility of concurrent infection of gut commensal bacteria in asthmatic patients requiring long-term oral corticosteroid administration.https://doi.org/10.1186/s13099-023-00574-9Citrobacter koseriSevere asthmaAbdominal infectionOpportunistic pathogen |
| spellingShingle | Mo Xian Xiaolong Ji Mingyu Zhong Danhong Su Jing Guan Ruchong Chen Severe asthma patient with secondary Citrobacter koseri abdominal infection: first case report and review of the literature Gut Pathogens Citrobacter koseri Severe asthma Abdominal infection Opportunistic pathogen |
| title | Severe asthma patient with secondary Citrobacter koseri abdominal infection: first case report and review of the literature |
| title_full | Severe asthma patient with secondary Citrobacter koseri abdominal infection: first case report and review of the literature |
| title_fullStr | Severe asthma patient with secondary Citrobacter koseri abdominal infection: first case report and review of the literature |
| title_full_unstemmed | Severe asthma patient with secondary Citrobacter koseri abdominal infection: first case report and review of the literature |
| title_short | Severe asthma patient with secondary Citrobacter koseri abdominal infection: first case report and review of the literature |
| title_sort | severe asthma patient with secondary citrobacter koseri abdominal infection first case report and review of the literature |
| topic | Citrobacter koseri Severe asthma Abdominal infection Opportunistic pathogen |
| url | https://doi.org/10.1186/s13099-023-00574-9 |
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