Xanthine oxidoreductase activity is correlated with hepatic steatosis

Xanthine oxidoreductase activity is correlated with hepatic steatosis

Abstract The enzyme xanthine oxidoreductase (XOR) catalyzes the synthesis of uric acid (UA) from hypoxanthine and xanthine, which are products of purine metabolism starting from ribose-5-phosphate. Several studies suggested a relationship between hyperuricemia and hepatic steatosis; however, few pre...

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Main Authors: Chisako Yagi, Yoshiki Kusunoki, Taku Tsunoda, Takayo Murase, Takashi Nakamura, Keiko Osugi, Mana Ohigashi, Akiko Morimoto, Akio Miyoshi, Miki Kakutani-Hatayama, Kae Kosaka-Hamamoto, Manabu Kadoya, Kosuke Konishi, Takuhito Shoji, Hidenori Koyama
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-16688-0

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