Multimedia-based hormone therapy information program for patients with prostate cancer: the result of a randomized pilot study
Abstract Few studies have explored the feasibility and efficacy of a multimedia information intervention for patients with prostate cancer who are undergoing hormone therapy. Thus, the purpose of the study was to assess the feasibility, acceptability, and the preliminary results of a multimedia-base...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-12-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-50006-6 |
| _version_ | 1797371221909700608 |
|---|---|
| author | Ching-Hui Chien Kuan-Lin Liu Cheng-Keng Chuang Chun-Te Wu Ying-Hsu Chang Kai-Jie Yu |
| author_facet | Ching-Hui Chien Kuan-Lin Liu Cheng-Keng Chuang Chun-Te Wu Ying-Hsu Chang Kai-Jie Yu |
| author_sort | Ching-Hui Chien |
| collection | DOAJ |
| description | Abstract Few studies have explored the feasibility and efficacy of a multimedia information intervention for patients with prostate cancer who are undergoing hormone therapy. Thus, the purpose of the study was to assess the feasibility, acceptability, and the preliminary results of a multimedia-based hormone therapy information program (HTIP) on positive thinking and quality of life (QOL; primary outcomes) as well as social support and self-efficacy (secondary outcomes) of patients with prostate cancer. Patients with prostate cancer who were receiving hormone therapy were recruited from hospitals. After completing the pre-test questionnaire, patients were randomly divided into the multimedia information group (MIG; n = 40) and the control group (CG; n = 40). Patients in the MIG received a multimedia-based HTIP once a week for 6 weeks. Data were collected at 8 and 12 weeks after the pre-test. Measurement variables included positive thinking, QOL, social support, self-efficacy, and satisfaction with the program. The recruitment rate and retention rate were calculated for assessment of feasibility. The study had a 96.3% retention rate, and patients in the MIG were satisfied with the program. Preliminary results showed that, compared with those in the CG, patients in the MIG tended to exhibit higher positive thinking, prostate cancer-specific QOL, and social support at 8 weeks and 12 weeks after pre-test; however, the effect did not reach a statistically significant level. A multimedia-based HTIP is considered feasible and acceptable in patients with prostate cancer who underwent hormone therapy. Further research with a larger sample size, patients with high homogeneity in early-stage disease and long-term follow-up is needed to assess the efficacy of the intervention program. Trial registration: ClinicalTrials.gov (NCT04693910); Registered 05/01/2021. |
| first_indexed | 2024-03-08T18:15:44Z |
| format | Article |
| id | doaj.art-926c65cd8a83486da74955cf81e3c11b |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-08T18:15:44Z |
| publishDate | 2023-12-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-926c65cd8a83486da74955cf81e3c11b2023-12-31T12:09:30ZengNature PortfolioScientific Reports2045-23222023-12-0113111610.1038/s41598-023-50006-6Multimedia-based hormone therapy information program for patients with prostate cancer: the result of a randomized pilot studyChing-Hui Chien0Kuan-Lin Liu1Cheng-Keng Chuang2Chun-Te Wu3Ying-Hsu Chang4Kai-Jie Yu5School of Nursing, National Taipei University of Nursing and Health SciencesDivision of Urology, Department of Surgery, Chang Gung Memorial Hospital at KeelungDivision of Urology, Department of Surgery, Chang Gung Memorial Hospital at LinkouDivision of Urology, Department of Surgery, Chang Gung Memorial Hospital at LinkouCollege of Medicine, Chang Gung UniversityDivision of Urology, Department of Surgery, Chang Gung Memorial Hospital at LinkouAbstract Few studies have explored the feasibility and efficacy of a multimedia information intervention for patients with prostate cancer who are undergoing hormone therapy. Thus, the purpose of the study was to assess the feasibility, acceptability, and the preliminary results of a multimedia-based hormone therapy information program (HTIP) on positive thinking and quality of life (QOL; primary outcomes) as well as social support and self-efficacy (secondary outcomes) of patients with prostate cancer. Patients with prostate cancer who were receiving hormone therapy were recruited from hospitals. After completing the pre-test questionnaire, patients were randomly divided into the multimedia information group (MIG; n = 40) and the control group (CG; n = 40). Patients in the MIG received a multimedia-based HTIP once a week for 6 weeks. Data were collected at 8 and 12 weeks after the pre-test. Measurement variables included positive thinking, QOL, social support, self-efficacy, and satisfaction with the program. The recruitment rate and retention rate were calculated for assessment of feasibility. The study had a 96.3% retention rate, and patients in the MIG were satisfied with the program. Preliminary results showed that, compared with those in the CG, patients in the MIG tended to exhibit higher positive thinking, prostate cancer-specific QOL, and social support at 8 weeks and 12 weeks after pre-test; however, the effect did not reach a statistically significant level. A multimedia-based HTIP is considered feasible and acceptable in patients with prostate cancer who underwent hormone therapy. Further research with a larger sample size, patients with high homogeneity in early-stage disease and long-term follow-up is needed to assess the efficacy of the intervention program. Trial registration: ClinicalTrials.gov (NCT04693910); Registered 05/01/2021.https://doi.org/10.1038/s41598-023-50006-6 |
| spellingShingle | Ching-Hui Chien Kuan-Lin Liu Cheng-Keng Chuang Chun-Te Wu Ying-Hsu Chang Kai-Jie Yu Multimedia-based hormone therapy information program for patients with prostate cancer: the result of a randomized pilot study Scientific Reports |
| title | Multimedia-based hormone therapy information program for patients with prostate cancer: the result of a randomized pilot study |
| title_full | Multimedia-based hormone therapy information program for patients with prostate cancer: the result of a randomized pilot study |
| title_fullStr | Multimedia-based hormone therapy information program for patients with prostate cancer: the result of a randomized pilot study |
| title_full_unstemmed | Multimedia-based hormone therapy information program for patients with prostate cancer: the result of a randomized pilot study |
| title_short | Multimedia-based hormone therapy information program for patients with prostate cancer: the result of a randomized pilot study |
| title_sort | multimedia based hormone therapy information program for patients with prostate cancer the result of a randomized pilot study |
| url | https://doi.org/10.1038/s41598-023-50006-6 |
| work_keys_str_mv | AT chinghuichien multimediabasedhormonetherapyinformationprogramforpatientswithprostatecancertheresultofarandomizedpilotstudy AT kuanlinliu multimediabasedhormonetherapyinformationprogramforpatientswithprostatecancertheresultofarandomizedpilotstudy AT chengkengchuang multimediabasedhormonetherapyinformationprogramforpatientswithprostatecancertheresultofarandomizedpilotstudy AT chuntewu multimediabasedhormonetherapyinformationprogramforpatientswithprostatecancertheresultofarandomizedpilotstudy AT yinghsuchang multimediabasedhormonetherapyinformationprogramforpatientswithprostatecancertheresultofarandomizedpilotstudy AT kaijieyu multimediabasedhormonetherapyinformationprogramforpatientswithprostatecancertheresultofarandomizedpilotstudy |