Subnormothermic Ex Vivo Porcine Kidney Perfusion Improves Energy Metabolism: Analysis Using 31P Magnetic Resonance Spectroscopic Imaging

Subnormothermic Ex Vivo Porcine Kidney Perfusion Improves Energy Metabolism: Analysis Using 31P Magnetic Resonance Spectroscopic Imaging

Background. The ideal preservation temperature for donation after circulatory death kidney grafts is unknown. We investigated whether subnormothermic (22 °C) ex vivo kidney machine perfusion could improve kidney metabolism and reduce ischemia-reperfusion injury. Methods. To mimic donation after circ...

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Bibliographic Details
Main Authors: Thomas Agius, MS, Julien Songeon, MS, Antoine Klauser, PhD, Florent Allagnat, PhD, Grégoire Longchamp, MD, Raphael Ruttimann, BS, Arnaud Lyon, MD, Julijana Ivaniesevic, PhD, Raphael Meier, MD, PhD, Sébastien Déglise, MD, James F. Markmann, MD, PhD, Korkut Uygun, PhD, Leo Buhler, MD, Christian Toso, MD, PhD, Jean-Marc Corpataux, MD, Francois Lazeyras, PhD, Alban Longchamp, MD, PhD
Format: Article
Language:English
Published: Wolters Kluwer 2022-10-01
Series:Transplantation Direct
Online Access:http://journals.lww.com/transplantationdirect/fulltext/10.1097/TXD.0000000000001354

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