Negative dietary cation-anion difference and amount of calcium in prepartum diets: Effects on urine and serum minerals
Negative dietary cation-anion difference (DCAD) diets fed prepartum induce a compensated metabolic acidosis, which stimulates metabolic Ca flux before calving and decreases clinical and subclinical hypocalcemia after calving. Effects of low or high dietary Ca in these diets are unclear. Our objectiv...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-11-01
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| Series: | JDS Communications |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666910223000753 |
| _version_ | 1827762386594955264 |
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| author | K.M. Glosson X. Zhang K.P. Zanzalari S.S. Bascom A.D. Rowson Z. Wang J.K. Drackley |
| author_facet | K.M. Glosson X. Zhang K.P. Zanzalari S.S. Bascom A.D. Rowson Z. Wang J.K. Drackley |
| author_sort | K.M. Glosson |
| collection | DOAJ |
| description | Negative dietary cation-anion difference (DCAD) diets fed prepartum induce a compensated metabolic acidosis, which stimulates metabolic Ca flux before calving and decreases clinical and subclinical hypocalcemia after calving. Effects of low or high dietary Ca in these diets are unclear. Our objective was to determine the effects of inducing a prepartum metabolic acidosis and the amount of dietary Ca on urinary mineral excretion and serum mineral concentrations during the transition period in multiparous Holstein cows (n = 81). Treatment diets fed during the last 28 d before calving were (1) positive DCAD, +6 mEq/100 g of dry matter (DM), target urine pH >7.5, low dietary Ca (0.40% DM; CON); (2) negative DCAD, −24 mEq/100 g of DM, target urine pH 5.5 to 6.0, low dietary Ca (0.40% DM; ND); or (3) negative DCAD, −24 mEq/100 g of DM, target urine pH 5.5 to 6.0, high dietary Ca (2.0% DM; NDCA). Urine was sampled on −21, −14, −7, +1, +2, and +7 d relative to calving. Blood samples were collected on d −30, −21, −14, −7, −4, −2, −1, 0, 1, 2, and 4 relative to parturition. Preplanned treatment contrasts were (1) CON versus ND and NDCA, and (2) ND versus NDCA. Cows fed ND or NDCA had increased urinary volume and excretion of Ca, Cl, and SO4−2, along with decreased excretion of K. Supplementation of Ca to the acidogenic diet increased urinary excretion of Ca at d −21, but this difference lessened as cows approached parturition. Additional Ca increased prepartum urinary excretion of K and Cl. Differences in excretion decreased quickly after parturition, although urinary excretion of Cl remained greater for cows previously fed negative DCAD diets. Acidogenic diets increased serum K and Cl concentrations prepartum. Supplemental Ca decreased serum P relative to ND. During d 0 to 4, serum P and K were greater for cows fed ND or NDCA than for cows fed CON; these differences disappeared by d 4. Acidogenic diets increased serum Ca by increasing Ca flux and excretion in urine. Supplemental Ca in the acidogenic diet modestly increased Ca excretion early in the close-up period. |
| first_indexed | 2024-03-11T10:29:51Z |
| format | Article |
| id | doaj.art-9278a9090dd94361ab9ad8b3fe2f82a9 |
| institution | Directory Open Access Journal |
| issn | 2666-9102 |
| language | English |
| last_indexed | 2024-03-11T10:29:51Z |
| publishDate | 2023-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JDS Communications |
| spelling | doaj.art-9278a9090dd94361ab9ad8b3fe2f82a92023-11-15T04:12:13ZengElsevierJDS Communications2666-91022023-11-0146449453Negative dietary cation-anion difference and amount of calcium in prepartum diets: Effects on urine and serum mineralsK.M. Glosson0X. Zhang1K.P. Zanzalari2S.S. Bascom3A.D. Rowson4Z. Wang5J.K. Drackley6Department of Animal Sciences, University of Illinois, Urbana, IL 61801; Phibro Animal Health Corporation, Teaneck, NJ 07666-6712Institute of Animal Nutrition, Key Laboratory of Low Carbon Culture and Safety Production in Cattle in Sichuan, Sichuan Agricultural University, Chengdu, Sichuan, P. R. China 611130Phibro Animal Health Corporation, Teaneck, NJ 07666-6712Phibro Animal Health Corporation, Teaneck, NJ 07666-6712Phibro Animal Health Corporation, Teaneck, NJ 07666-6712Institute of Animal Nutrition, Key Laboratory of Low Carbon Culture and Safety Production in Cattle in Sichuan, Sichuan Agricultural University, Chengdu, Sichuan, P. R. China 611130Department of Animal Sciences, University of Illinois, Urbana, IL 61801; Corresponding authorNegative dietary cation-anion difference (DCAD) diets fed prepartum induce a compensated metabolic acidosis, which stimulates metabolic Ca flux before calving and decreases clinical and subclinical hypocalcemia after calving. Effects of low or high dietary Ca in these diets are unclear. Our objective was to determine the effects of inducing a prepartum metabolic acidosis and the amount of dietary Ca on urinary mineral excretion and serum mineral concentrations during the transition period in multiparous Holstein cows (n = 81). Treatment diets fed during the last 28 d before calving were (1) positive DCAD, +6 mEq/100 g of dry matter (DM), target urine pH >7.5, low dietary Ca (0.40% DM; CON); (2) negative DCAD, −24 mEq/100 g of DM, target urine pH 5.5 to 6.0, low dietary Ca (0.40% DM; ND); or (3) negative DCAD, −24 mEq/100 g of DM, target urine pH 5.5 to 6.0, high dietary Ca (2.0% DM; NDCA). Urine was sampled on −21, −14, −7, +1, +2, and +7 d relative to calving. Blood samples were collected on d −30, −21, −14, −7, −4, −2, −1, 0, 1, 2, and 4 relative to parturition. Preplanned treatment contrasts were (1) CON versus ND and NDCA, and (2) ND versus NDCA. Cows fed ND or NDCA had increased urinary volume and excretion of Ca, Cl, and SO4−2, along with decreased excretion of K. Supplementation of Ca to the acidogenic diet increased urinary excretion of Ca at d −21, but this difference lessened as cows approached parturition. Additional Ca increased prepartum urinary excretion of K and Cl. Differences in excretion decreased quickly after parturition, although urinary excretion of Cl remained greater for cows previously fed negative DCAD diets. Acidogenic diets increased serum K and Cl concentrations prepartum. Supplemental Ca decreased serum P relative to ND. During d 0 to 4, serum P and K were greater for cows fed ND or NDCA than for cows fed CON; these differences disappeared by d 4. Acidogenic diets increased serum Ca by increasing Ca flux and excretion in urine. Supplemental Ca in the acidogenic diet modestly increased Ca excretion early in the close-up period.http://www.sciencedirect.com/science/article/pii/S2666910223000753 |
| spellingShingle | K.M. Glosson X. Zhang K.P. Zanzalari S.S. Bascom A.D. Rowson Z. Wang J.K. Drackley Negative dietary cation-anion difference and amount of calcium in prepartum diets: Effects on urine and serum minerals JDS Communications |
| title | Negative dietary cation-anion difference and amount of calcium in prepartum diets: Effects on urine and serum minerals |
| title_full | Negative dietary cation-anion difference and amount of calcium in prepartum diets: Effects on urine and serum minerals |
| title_fullStr | Negative dietary cation-anion difference and amount of calcium in prepartum diets: Effects on urine and serum minerals |
| title_full_unstemmed | Negative dietary cation-anion difference and amount of calcium in prepartum diets: Effects on urine and serum minerals |
| title_short | Negative dietary cation-anion difference and amount of calcium in prepartum diets: Effects on urine and serum minerals |
| title_sort | negative dietary cation anion difference and amount of calcium in prepartum diets effects on urine and serum minerals |
| url | http://www.sciencedirect.com/science/article/pii/S2666910223000753 |
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