APC Promoter Methylation in Gastrointestinal Cancer

The adenomatous polyposis coli (APC) gene, known as tumor suppressor gene, has the two promoters 1A and 1B. Researches on APC have usually focused on its loss-of-function variants causing familial adenomatous polyposis. Hypermethylation, however, which is one of the key epigenetic alterations of the...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Lila Zhu, Xinyu Li, Ying Yuan, Caixia Dong, Mengyuan Yang
स्वरूप: लेख
भाषा:English
प्रकाशित: Frontiers Media S.A. 2021-04-01
श्रृंखला:Frontiers in Oncology
विषय:
ऑनलाइन पहुंच:https://www.frontiersin.org/articles/10.3389/fonc.2021.653222/full