The Arginine Deiminase Pathway Impacts Antibiotic Tolerance during Biofilm-Mediated <named-content content-type="genus-species">Streptococcus pyogenes</named-content> Infections

The Arginine Deiminase Pathway Impacts Antibiotic Tolerance during Biofilm-Mediated <named-content content-type="genus-species">Streptococcus pyogenes</named-content> Infections

ABSTRACT Bacterial biofilms are responsible for a variety of serious human infections and are notoriously difficult to treat due to their recalcitrance to antibiotics. Further work is necessary to elicit a full understanding of the mechanism of this antibiotic tolerance. The arginine deiminase (ADI)...

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Bibliographic Details
Main Authors: Jeffrey A. Freiberg, Yoann Le Breton, Janette M. Harro, Devon L. Allison, Kevin S. McIver, Mark E. Shirtliff
Format: Article
Language:English
Published: American Society for Microbiology 2020-08-01
Series:mBio
Subjects:
Streptococcus pyogenes
antibiotic tolerance
arginine deiminase
biofilms
group A Streptococcus
Online Access:https://journals.asm.org/doi/10.1128/mBio.00919-20

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