Intrathyroidal feedforward and feedback network regulating thyroid hormone synthesis and secretion

Intrathyroidal feedforward and feedback network regulating thyroid hormone synthesis and secretion

Thyroid hormones (THs), including T4 and T3, are produced and released by the thyroid gland under the stimulation of thyroid-stimulating hormone (TSH). The homeostasis of THs is regulated via the coordination of the hypothalamic-pituitary-thyroid axis, plasma binding proteins, and local metabolism i...

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Bibliographic Details
Main Authors: Li Jing, Qiang Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Endocrinology
Subjects:
thyroid hormone
feedforward
feedback
thyrocyte
intrathyroidal regulation
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.992883/full

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